Stage IIB Prostate Cancer Clinical Trial
Official title:
A Prospective Investigation of Near Infrared Fluorescence Imaging of Pelvic Lymph Nodes Using Indocyanine Green on the da Vinci Surgical System During Radical Prostatectomy and Pelvic Lymphadenectomy for Localized Prostate Cancer
This clinical trial studies diffuse optical imaging with indocyanine green solution in imaging pelvic lymph nodes in patients with stage II prostate cancer undergoing surgery. Indocyanine green solution is a special dye that can help doctors see the lymph nodes and blood vessels during surgery when visualized under diffuse optical imaging. Indocyanine green solution may improve the ability to detect lymph nodes and may lead to improved accuracy of lymph node removal.
PRIMARY OBJECTIVES:
I. To determine the ability of indocyanine green (indocyanine green solution) (ICG) to
highlight pelvic lymphatic tissue with fluorescence during robot assisted radical
prostatectomy using near infrared fluorescence (diffuse optical imaging).
SECONDARY OBJECTIVES:
I. To evaluate the ability of this technique to improve lymph node yield, providing a
potential therapeutic benefit to these patients by removing additional lymph nodes that may
otherwise have been missed.
OUTLINE:
Patients receive indocyanine green transperineally and undergo diffuse optical imaging during
robot-assisted laparoscopic radical prostatectomy with bilateral lymph node dissection using
the da Vinci Robotic Surgical System.
After completion of study treatment, patients are followed up for 1-2 weeks.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02217709 -
Phenelzine Sulfate in Treating Patients With Non-metastatic Recurrent Prostate Cancer
|
Phase 2 | |
Completed |
NCT03233555 -
Extended Cancer Education for Longer-Term Survivors in Primary Care for Patients With Stage I-II Breast or Prostate Cancer or Stage I-III Colorectal Cancer
|
N/A | |
Completed |
NCT00103194 -
Lapatinib Ditosylate in Treating Patients With a Rising PSA Indicating Recurrent Prostate Cancer
|
Phase 2 | |
Completed |
NCT02250014 -
The Immuno-Response to Primary Cryotherapy for the Treatment of Prostate Cancer
|
Phase 1 | |
Active, not recruiting |
NCT01655836 -
High-Dose Rate Brachytherapy and Stereotactic Body Radiation Therapy in Treating Patients With Prostate Cancer
|
Phase 1 | |
Terminated |
NCT01340599 -
Defined Green Tea Catechin Extract in Treating Patients With Localized Prostate Cancer Undergoing Surgery
|
Phase 2 | |
Active, not recruiting |
NCT01823562 -
Aborption and Metabolism of Lyophilized Black Raspberry Food Products in Men With Prostate Cancer Undergoing Surgery
|
Phase 1 | |
Active, not recruiting |
NCT01923506 -
Stereotactic Body Radiation Therapy in Treating Patients With Prostate Cancer After Undergoing Surgery
|
Phase 1 | |
Completed |
NCT01433913 -
Metformin Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery
|
Phase 2 | |
Completed |
NCT00589472 -
Androgen Deprivation Therapy and Vorinostat Followed by Radical Prostatectomy in Treating Patients With Localized Prostate Cancer
|
Phase 2 | |
Active, not recruiting |
NCT02176902 -
Low-Fat Diet and Fish Oil in Men on Active Surveillance for Prostate Cancer
|
N/A | |
Completed |
NCT01731912 -
Degarelix Acetate Before and During Radiation Therapy in Treating Patients With Prostate Cancer
|
N/A | |
Completed |
NCT01656304 -
Bevacizumab in Treating Patients With Relapsed Prostate Cancer That Did Not Respond to Hormone Therapy
|
Phase 2 | |
Recruiting |
NCT03880422 -
Nutrition and Exercise Interventions in Reducing Androgen Deprivation Therapy-Induced Obese Frailty in Prostate Cancer Survivors
|
N/A | |
Active, not recruiting |
NCT02446366 -
Hypofractionated Stereotactic Body Radiation Therapy for Patients With Prostate Cancer That Was Removed by Surgery
|
N/A | |
Completed |
NCT02048150 -
Intra-operative Optical Imaging With MDX1201-A488 in Patients With Prostate Cancer
|
Phase 1 | |
Withdrawn |
NCT01555632 -
Atorvastatin Calcium in Preventing Metabolic Syndrome in Prostate Cancer Patients Receiving Androgen-Deprivation Therapy
|
N/A | |
Withdrawn |
NCT01859689 -
Internal Radiation Therapy in Treating Patients With Low-Risk Prostate Cancer
|
Phase 2 | |
Completed |
NCT01023061 -
Abiraterone Acetate, Prednisone, and Leuprolide Acetate or Goserelin Before and During Radiation Therapy in Treating Patients With Localized or Locally Advanced Prostate Cancer
|
Phase 2 | |
Completed |
NCT00956163 -
Whole Body Fluorine F 18 Sodium Fluoride PET/CT Scan and Whole Body MRI in Finding Bone Metastases in Patients With Prostate Cancer
|
Phase 0 |