Squamous Cell Carcinoma of Oropharynx Clinical Trial
Official title:
Usefulness of Narrow-band Imaging to Estimate the Superficial Spread of Squamous Cell Carcinomas in Oropharynx, Hypopharynx and Larynx
The aim of this study is to prospectively determine if the use of NBI endoscopy modifies the superficial extension of these tumors.
Several studies have already showed the interest of the use of NBI for the early diagnosis of
malignancies of the upper aerodigestive tract. For all tumors, the most accurate evaluation
of its limits is very important to perform the best strategy of treatment. If surgery seems
to be the best option, surgical margins must be widely healthy. Despite the systematic
transnasal flexible endoscopy with white lamp followed by laryngoscopy under general
anesthesia (LGA) and tomodensitometric evaluation, surgical margins can be unhealthy (in situ
carcinoma or dysplasia). We propose to evaluate if the use of the NBI could be useful to
determine the superficial spread of squamous cell carcinomas in these locations.
To April 2013 to Mars 2015, all patients with a suspicion of squamous cell carcinoma of the
oropharynx, hypopharynx or larynx and whom a LGA are expected, are included. The day before
the LGA, two endoscopies by two different physicians were performed for each patients and
recorded: the first one with white light and the second one with NBI. All results are noted
on a schema. Superficial extension or synchronous lesions showed by NBI are analysed and
compared with with lamp technic.
After surgery, surgical margins were evaluated and healthy margins were measured.
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