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Spondylolisthesis clinical trials

View clinical trials related to Spondylolisthesis.

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NCT ID: NCT05648474 Recruiting - Spondylolisthesis Clinical Trials

Intraoperative Monitoring for the Lateral Lumbar Interbody Fusion Procedure

Start date: July 13, 2022
Phase:
Study type: Observational

This study is designed to evaluate the clinical utility of a known intraoperative neuromonitoring modality (SSEP) using saphenous nerve as the site of stimulation to identify changes to the lumbar nerves which may be at risk during the lateral lumbar interbody fusion (LLIF) procedure.

NCT ID: NCT05638399 Recruiting - Osteopenia Clinical Trials

Denosumab vs Zoledronate After Lumbar Fusion

Start date: January 15, 2020
Phase: Phase 3
Study type: Interventional

The aim of the study was to compare denosumab and zoledronate efficacy in bone mass, bone turnover markers (BTMs), Visual Analogue Scale (VAS) for leg and back, EuroQol Five-Dimension (EQ-5D) scores, Quality of Life Questionnaire of the European Foundation for Osteoporosis-31 (QUALEFFO-31) scores, and Roland-Morris Disability Functioning Questionnaire (RMDQ) scores, secondary fracture, complications and adverse events after lumbar fusion.

NCT ID: NCT05610397 Not yet recruiting - Clinical trials for Degenerative Disc Disease

Retrospective Study With Patients Treated With STALIF® C or M and Ti or FLX Implants for 1 and 2 Levels

Stalif
Start date: April 24, 2023
Phase:
Study type: Observational

This is a Retrospective, Observational Multi-Center study, utilizing patients diagnosed with up to a Grade1 spondylolisthesis or retrolisthesis or symptomatic degenerative disc disease and treated with STALIF® C, or M, Ti and/or FLX implants at one or two levels.

NCT ID: NCT05583864 Recruiting - Spondylolisthesis Clinical Trials

Lumbar Fusion With Porous Versus Non-Porous Cages

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

The objective of this single site, randomized controlled trial is to assess and compare radiographic and clinical outcomes in patients who are to undergo lumbar interbody fusion procedures (TLIF), supplemented with pedicle screw instrumentation, using one of the following interventions: 1. Porous titanium cages 2. Non-porous titanium-coated poly-ether-ether-ketone (PEEK) cages.

NCT ID: NCT05566704 Completed - Clinical trials for Degenerative Disc Disease

Retrospective Modulus ALIF Study

Start date: August 18, 2022
Phase:
Study type: Observational

The primary objective of this study is to evaluate the safety and performance of the Modulus ALIF System in patients undergoing anterior lumbar interbody fusion (ALIF) as measured by reported complications, radiographic outcomes, and patient-reported outcomes.

NCT ID: NCT05565456 Recruiting - Spondylolisthesis Clinical Trials

Intercorporal Bone Graft Measurement Study

Start date: December 2, 2022
Phase:
Study type: Observational

Instrumented lumbar fusion surgery is often accompanied by interbody fusion using an autologous bone graft that is supposed to expand and remodel to achieve a rigid and lasting bony construction between two vertebrae. However, there is a dearth of knowledge regarding the process of biological remodelling of intercorporal bone grafts. Also, a valid and reliable assessment of fusion status remains challenging because there is no objective tool available to quantify the bone remodelling process. CT-based Hounsfield Units correlate with Bone Mineral Density and can be used as a proxy to establish trajectories over time to assess changes in bone mineral density from the bone graft.

NCT ID: NCT05538416 Not yet recruiting - Clinical trials for Degenerative Spondylolisthesis

Short-term Clinical Outcome of Cortical Bone Trajectory Compared With the Traditional "Open" and Minimal Invasive Posterior Lumbar Interbody Fusion

Start date: September 2022
Phase:
Study type: Observational

A combined prospective cohort study and retrospective analysis of previously collected data. Three different techniques for posterior lumbar interbody fusion (PLIF) are compared: CBT-PLIF, MI-PLIF and open PLIF. A total of 180 patients are included, who will be followed up to 6 weeks postoperatively.

NCT ID: NCT05527145 Recruiting - Clinical trials for Lumbar Spinal Stenosis

Spinal Stenosis and Listhesis Treated With Percutaneous Interspinous Spacer: a Non-surgical Trial

Start date: September 2024
Phase: N/A
Study type: Interventional

Symptomatic lumbar spinal stenosis is the most common indication for spinal surgery. However, more than one-third of the patients undergoing surgery for lumbar stenosis report dissatisfaction with the results. On the other hand, conservative treatment has shown positive results in some cases. This trial will compare the outcomes of surgical versus non-surgical treatment for lumbar stenosis.

NCT ID: NCT05480267 Not yet recruiting - Clinical trials for Lumbar Spondylolisthesis

A RCT of UBE vs. MIS-TLIF in Lumbar Spondylolisthesis

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

Unilateral biportal endoscopy (UBE) is a new spinal minimally invasive technique improved for the treatment of lumbar spondylolisthesis (LSP). The present study aims to establish a multicenter, large sample, randomized controlled study to explore the technical advantages and surgical indications of this new technique in the treatment of LSP by comparing with the classical minimally invasive posterior spinal interbody fusion; to compare the postoperative clinical and imaging results and analyze the surgical complications and preventive measures.

NCT ID: NCT05464134 Not yet recruiting - Clinical trials for Lumbar Spondylolisthesis

Incidence of Lumbar Spondylolisthesis in Patients Candidate for TKR

Start date: May 2023
Phase:
Study type: Observational

This study aims to detect the incidence of spondylolisthesis in patients candidate for Total knee replacement (TKR) and to investigate the effect of TKR on the course of low back pain.