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Clinical Trial Summary

The term Spondylodiscitis (SD) involves infection of the vertebra (Spondylitis), infection of the intervertebral disc (Discitis), or both (Spondylodiscitis) Spondylodiscitis is a rare disease accounting for 2.7% of all cases of pyogenic osteomyelitis, with incidence varying from 1 per 100,000/year to 1 per 250,000/year However, there is evidence that the incidence is rising due to longer life expectancy for patients with increasing incidence of chronic debilitating disease including diabetes mellitus, malignancies ,(Human Immunodeficiency Virus (HIV)/ Acquired Immunodeficiency Syndrome (AIDs) , immunosuppressive therapy, increasing numbers of Intravenous drug users , and spinal surgeries. Pathogens can reach the spine either by: hematogenous spread, direct external inoculation, or spread from contiguous tissues harboring these pathogens. The hematogenous route is the predominant one, allowing seeding of infection from distant sites into the vertebral column. Since spondylodiscitis has not been studied in a clinical trial at our hospital, and information about this disease has come from retrospective case series and isolated cases. In this study, we present our prospectively collected patient clinical and epidemiological data in order to provide a proper management


Clinical Trial Description

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Study Design


Related Conditions & MeSH terms


NCT number NCT05806905
Study type Observational
Source Assiut University
Contact Mohammed G Hassan, Professor
Phone 01001843084
Email m.gamal@aun.edu.eg
Status Recruiting
Phase
Start date September 1, 2022
Completion date September 2024

See also
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Not yet recruiting NCT04436328 - Conservative Versus Surgical Treatment of Native Vertebral Osteomyelitis N/A
Not yet recruiting NCT04749082 - Follow up Patients With Thoracolumbar Spondylodiscitis Surgically Treated by Posterior Approach
Completed NCT05486494 - Spine Registry University Hospital of Cologne- Department of Orthopedics
Completed NCT04655950 - Immobilization and Neurological Complications in Patients With Vertebral Osteomyelitis.
Active, not recruiting NCT03524209 - CORset Versus OstéoSynthese in Adult Pyogenic Spondylodiscitis N/A