Clinical Trials Logo
  1. Home
  2. Spinal Tumor
  3. NCT05106179
  4. Details
NCT05106179 Clinical Trial

The Efficacy and Safety of Beta-blockers Drugs in Adults With Spinal Hemangioma

Spinal Tumor Clinical Trial

Official title:
The Efficacy and Safety of Beta-blockers Drugs in Adults With Spinal Hemangioma: a Prospective Cohort Study

Clinical Trial Details — Status: Enrolling by invitation

Administrative data
NCT number NCT05106179
Other study ID # S_Hemangioma
Secondary ID
Status Enrolling by invitation
Phase Phase 4
First received
Last updated
Start date December 2021
Est. completion date December 2023

Study information
Verified date November 2021
Source Center for Vascular Pathology, Moscow
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Spinal hemangioma is one of the most common benign vertebral tumours. Being mostly asymptomatic, it is still associated with a pain syndrome especially if encroaches into the neural canal. This study is organised to evaluate the efficacy and safety of β-blockers drugs in adults with spinal hemangioma.

Recruitment information / eligibility
Status Enrolling by invitation
Enrollment 1000
Est. completion date December 2023
Est. primary completion date December 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years to 50 Years
Eligibility Inclusion Criteria: - vertebral hemangioma Exclusion Criteria: - symptomatic bradycardia - AV block - decompensated heart failure - asthma

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Atenolol Pill
Atenolol is a second-generation hydrophilic ß-1-selective adrenergic antagonist, which is primarily metabolised by the kidneys.
• Propranolol Pill
Propranolol is highly lipophilic, nonselective ß-blockers, which is primarily metabolised by the liver.

Locations
Country Name City State
Russian Federation The Vascular Anomalies Center (VAC) "Hemangioma" Moscow

Sponsors (1)
Lead Sponsor Collaborator
Center for Vascular Pathology, Moscow

Country where clinical trial is conducted

Russian Federation, 

Outcome
Type Measure Description Time frame Safety issue
Primary Reducing tumor growth MRI 3 months
Primary Reducing tumor MRI 6 months
Primary Life-quality Valid questionnaires based on the ones, approved by EuroQol Organization 3 months and 6 months
See also
  Status Clinical Trial Phase
Recruiting NCT03668522 - Clinical Research of H3F3AK27M in Spinal Glioma and Its Impact on TMZ Chemoradiotherapy
Active, not recruiting NCT03956537 - PMCF Neo Pedicle Screw and Cage Systems
Completed NCT03585699 - Percutaneous Fluoroscopic vs CT Guided Core Needle Biopsy for Spinal Infection and Tumor N/A
Completed NCT04578691 - Study to Evaluate the Safety and Clinical Outcome of Using Navigation System in Pedicle Screw Placement in Spine Surgery N/A
Withdrawn NCT03893110 - Carbon PEEK Versus Titanium Pedicle Screws in the Treatment of Spinal Tumors N/A
Not yet recruiting NCT06161974 - Study of Olutasidenib and Temozolomide in HGG Phase 2
Completed NCT01624220 - A Prospective Study Using Implanted Fiducial Markers to Assess Treatment Accuracy and Esophageal Toxicity in Spinal Stereotactic Body Radiation Therapy N/A
Not yet recruiting NCT05369689 - Stereotactic Radiosurgery Prognosis Assessment for Spinal Tumors Based on Radiomics
Recruiting NCT05296889 - Post-Market Clinical Follow-Up Study on the Safety and Performance of Ennovate® Cervical
Completed NCT02252185 - A Clinical Study of a Spine Fusion System in Vertebral Body Fusion Surgery N/A
Recruiting NCT06120426 - En Bloc Resection Versus Separation Surgery Combined With Radiotherapy for the Treatment of Spinal Oligometastatic Tumor.
Recruiting NCT05170815 - Clariance ErYs Registry
Active, not recruiting NCT03052738 - Medical Marijuana in the Pediatric Central Nervous System Tumor Population
Completed NCT04952818 - The Value of Preoperative Diagnosis and Prognostic Prediction Based on Radiomics of Giant Cell Tumor of Spine
Recruiting NCT03398915 - The European Robotic Spinal Instrumentation (EUROSPIN) Study
Recruiting NCT04217525 - Duke Spine Outcome Study (DSOS)
Completed NCT02613390 - Safety Evaluation of Intra-Operative MRI-Based Guidance for Laser Ablation of Epidural Metastasis N/A
Completed NCT02790294 - Optimal Timing of Postoperative Magnetic Resonance Imaging (MRI) in Patients With Extradural Spinal N/A
Not yet recruiting NCT05396222 - A Prospective Study of the Safety and Efficacy of 3D-printed Non-rigid Biomimetic Implant in Cervical and Thoracolumbar Spine N/A
Recruiting NCT05631002 - Chemical Shift Encoding-based Water-fat Magnetic Resonance Imaging in Spinal Tumors