Solitary Pulmonary Nodule Clinical Trial
Official title:
Mobile Lung Nodule Observatory for Worldwide, Evidenced - Based Research
Patients with lung nodules may develop a variety of potentially severe symptoms. These symptoms may impact a patient's quality of life and lead to difficult treatment. Through this research program, the investigators want to understand the pathogenesis of the changes of these symptoms.
Lung nodules can manifest as single or multiple independent lung consolidation shadow in form
of quasi-circular. These lung nodules are surrounded by normal lung tissues, and will not
cause pulmonary atelectasis. In some early standards, all the quasi-circular shadows within
6cm found in lung are categorized as lung nodules. However, according to current standards,
the lesion within 3cm can be identified as lung nodules. With widespread use of lung cancer
CT screening, lung nodules were identified more and more frequently.
What is the optimal way to manage this CT finding? Should we adopt surgical removal or just
observation? An optimal solution is to determine a clearly defined standard of care that is
easy to learn. We propose a method called "three plus two". The 'Three' is a three-step
testing method, and the 'Two' means two alternative solutions. Three-step testing method
includes collecting medical history, non-invasive examination, and invasive examination. The
two alternative solutions are surgical removal and follow-up observation. We have
independently developed an application based on a smartphone platform. This platform will
provide a novel evidence-based research method for observing the dynamic evolution of the
lung nodules in patients. There have been no prior studies about managing this CT scan
finding, either in China or internationally.
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