Solitary Pulmonary Nodule Clinical Trial
Official title:
Mobile Lung Nodule Observatory for Worldwide, Evidenced - Based Research
Patients with lung nodules may develop a variety of potentially severe symptoms. These symptoms may impact a patient's quality of life and lead to difficult treatment. Through this research program, the investigators want to understand the pathogenesis of the changes of these symptoms.
Lung nodules can manifest as single or multiple independent lung consolidation shadow in form
of quasi-circular. These lung nodules are surrounded by normal lung tissues, and will not
cause pulmonary atelectasis. In some early standards, all the quasi-circular shadows within
6cm found in lung are categorized as lung nodules. However, according to current standards,
the lesion within 3cm can be identified as lung nodules. With widespread use of lung cancer
CT screening, lung nodules were identified more and more frequently.
What is the optimal way to manage this CT finding? Should we adopt surgical removal or just
observation? An optimal solution is to determine a clearly defined standard of care that is
easy to learn. We propose a method called "three plus two". The 'Three' is a three-step
testing method, and the 'Two' means two alternative solutions. Three-step testing method
includes collecting medical history, non-invasive examination, and invasive examination. The
two alternative solutions are surgical removal and follow-up observation. We have
independently developed an application based on a smartphone platform. This platform will
provide a novel evidence-based research method for observing the dynamic evolution of the
lung nodules in patients. There have been no prior studies about managing this CT scan
finding, either in China or internationally.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT05066776 -
Liquid Biopsy With PET/CT Versus PET/CT Alone in Diagnosis of Small Lung Nodules
|
||
| Completed |
NCT01958931 -
Evaluate the Utility of the ProLung Test as Adjunctive to CT Scan in the Diagnosis of Lung Cancer
|
N/A | |
| Recruiting |
NCT03528733 -
Feasibility of Multi-Energy Digital Radiography Detector for Lung Lesions Detection
|
N/A | |
| Completed |
NCT01566682 -
A Multi-Center Trial of the ProLung Test™
|
||
| Terminated |
NCT02983903 -
Cryobiopsy Versus Forceps Biopsy for Pulmonary Lesions
|
N/A | |
| Terminated |
NCT02050724 -
ThoHSpEkt Thoracoscopic Ectomy of Radioactively Marked Pulmonary Nodules With Free-hand SPECT
|
Phase 2 | |
| Not yet recruiting |
NCT04615156 -
18F-2-fluoro-2-deoxy-D-glucose in Positron Emission Tomography Computed Tomography
|
Phase 3 | |
| Recruiting |
NCT02726633 -
Evaluate the Utility of the ProLung China Test in the Diagnosis of Lung Cancer
|
N/A | |
| Active, not recruiting |
NCT02623712 -
The Watch the Spot Trial
|
N/A | |
| Recruiting |
NCT03568799 -
4-[18F]Fluoroglutamine PET/CT in Imaging Patients With Newly Diagnosed Lung Cancer or Indeterminate Pulmonary Nodules
|
N/A | |
| Not yet recruiting |
NCT02817048 -
Tubeless VATS for Peripheral Lung Nodule
|
N/A | |
| Recruiting |
NCT01149187 -
Usefulness of Interferon-gamma Release Assay in Diagnosing Pulmonary Nodules
|
N/A | |
| Completed |
NCT00925210 -
Bronchoscopic Approach to the Peripheral Lung Nodule - An Alternative Approach
|
Phase 2 | |
| Completed |
NCT02448225 -
18F-FSPG PET/CT in Imaging Patients With Newly Diagnosed Lung Cancer or Indeterminate Pulmonary Nodules
|
Phase 2 | |
| Recruiting |
NCT05171491 -
LungLB in Subjects Presenting With Indeterminate Pulmonary Nodules
|
||
| Terminated |
NCT04140474 -
Evaluation of the Archimedes ™ System for Transparenchymatous Access to Pulmonary Nodules.
|
N/A | |
| Withdrawn |
NCT05804435 -
iNod™ Ultrasound-Guided Needle Biopsy System Study
|
N/A | |
| Not yet recruiting |
NCT02653859 -
Evaluate the Auxiliary Diagnostic Value of Circulating Tumor Cells in Benign and Malignant Lung Nodules
|
N/A | |
| Completed |
NCT02832284 -
iNod System Human Feasibility Assessment
|
N/A | |
| Recruiting |
NCT02773992 -
Clinical Study of Three Plus Two Type Early Diagnosis of Pulmonary Nodules in Medical Internet of Things
|
N/A |