Solitary Pulmonary Nodule Clinical Trial
Official title:
Usefulness of Interferon-gamma Release Assay in Diagnosing Pulmonary Nodules
Among the causes of the solitary pulmonary nodule (SPN), benign causes including
tuberculosis was noted on 15 to 60 percents in various studies.
Although the characteristics of chest imaging is helpful in diagnosis and percutaneous
needle biopsy for pulmonary nodule has been represented high diagnostic yield in many
reports, but still surgical biopsy has been needed in definite diagnosis of pulmonary
nodules in many cases.
The aim of this study is to evaluate the usefulness of interferon-gamma release assay in
addition to the percutaneous needle biopsy, in diagnosis of pulmonary nodules.
Among the patients who failed to diagnosis by percutaneous needle biopsy and needed to have
Surgical biopsy, thirty percents of the patients were diagnosed as benign nodules and about
six percents were diagnosed as tuberculosis in Seoul National University Hospital during
2007-2008.
The investigators want to know whether conducting an interferon-gamma release assay in
addition to percutaneous needle biopsy is helpful in diagnosis of lung nodules.
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Observational Model: Case-Only, Time Perspective: Prospective
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