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Clinical Trial Summary

The purpose of this research study is to see if a high dose of ascorbate (Vitamin C), in combination with the chemotherapy drug gemcitabine, is safe and effective in adolescents with locally advanced unresectable or metastatic soft tissue and bone sarcomas


Clinical Trial Description

The primary objective of the expansion cohort of this pilot study is to evaluate preliminary evidence of anti-tumor activity of intravenous ascorbate in combination with gemcitabine as assessed by overall response rate to inform a subsequent Phase II trial. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04877587
Study type Interventional
Source University of Iowa
Contact
Status Withdrawn
Phase Early Phase 1
Start date January 2023
Completion date May 31, 2025

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