Smoking Dependence and Periodontitis

Smoking Clinical Trial

Official title:

Smoking Dependence (Fagerström) as a Relevant Indicator for Tobacco Related Studies in Periodontology.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03901066
• Other study ID #: File number: B707201419816
• Status: Completed
• Start date: September 3, 2014
• Est. completion date: July 2015

Study information

• Verified date: April 2019
• Source: University Hospital of Liege
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

The present study was designed as a, single-center, prospective cohort study focusing on the relationship between smoking status and the severity of periodontitis

Description:

The present study was designed as a, single-center, prospective cohort study focusing on the relationship between smoking status and the severity of periodontitis.

The research question was " How the Fagerström for nicotine dependence (FTND) and the number of cigarette cunsuption (NNC) are correlated to the severity of chronic periodontitis"? Thirty-four consecutive smoker patients presenting a chronic periodontitis were included in the study, and the smoking status was defined both by NCC and FTND.

Periodontal clinical parameters were correlated with NCC and FTND.

All the clinical periodontal parameters were recorded by a single periodontist (L.S). Periodontal assessments included: probing depth (PD), gingival recession (RD), clinical attachment level (CAL), bleeding on probing (BOP), plaque score index (PI), Furcation (Furc), tooth mobility and the percentage of sites of PD ≥ 6mm. A graduated manual periodontal probe was used to take measurements at the 6 sites of each tooth. BOP (%) and plaque score (%).

All the participants of the study respected the following inclusion criteria: 1/ smoker patients aged of minimum 18 years old, 2/ chronic periodontitis, 3/ presence of a minimum of 6 teeth at each arch, 4/ a minimum of 6 teeth with pocket depth of 5 mm, 5/ signed the informed consent. The exclusion criteria were: 1/ aggressive periodontitis, 2/ diabetes, 3/ connective tissue disease, 4/ pregnancy, 5/ radio-therapy, 6/ chemotherapy, 7/ psychological disease, 8/ previous periodontal therapy.

The patient smoking status was defined by FTND and NCC FTND scores were categorized in 3 groups

• scores < 4 for low nicotine dependence,

• scores = 4-5 for moderate nicotine dependence

• scores > 5 for high nicotine dependence.

The NCC s was classified in three levels of smokers as described in most of the periodontal studies:

• Number of cigarette smoking ≤ 10 per day for low consumption

• Number of cigarette smoking from 10 to 20 per day for moderate consumption

• Number of cigarette smoking > 20 per day for high cigarette consumption

Recruitment information / eligibility

• Status: Completed
• Enrollment: 34
• Est. completion date: July 2015
• Est. primary completion date: July 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• smoker patients aged of minimum 18 years old

• chronic periodontitis

• presence of a minimum of 6 teeth at each arch

• a minimum of 6 teeth with pocket depth of 5 mm

• signed the informed consent

Exclusion Criteria:

• aggressive periodontitis

• diabetes

• connective tissue disease

• pregnancy

• radio-therapy

• chemotherapy

• psychological disease

• previous periodontal therapy.

Related Conditions & MeSH terms

• Periodontitis
• Smoking

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital of Liege

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	effect of nicotine dependence level on periodontal outcomes	effect of nicotine dependence score on pocket depth (PD)	1 day