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Smoking, Tobacco clinical trials

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NCT ID: NCT03742154 Completed - Smoking Cessation Clinical Trials

Hollings Cancer Center Varenicline Sampling Study

Start date: December 3, 2018
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to learn what happens when people are given a free, 4-week, sample of varenicline, a smoking cessation medication. Investigators will look at quit attempts, changes in smoking, and attitude towards varenicline, in both smokers who want to quit and those who do not. Smoking use causes a number of deaths and diseases, including heart disease and cancer. All smokers are advised to quit. Varenicline (sometimes called Chantix), is a prescription medication approved by the US FDA. Many studies show that use of varenicline can help smokers quit smoking. Varenicline is a prescription medication, which usually means that people have to see a doctor to get it. This study examines a different way to deliver varenicline, delivered directly to participants for a few weeks, and without need to see a doctor. This method is called "varenicline sampling." The study is sponsored by the Hollings Cancer Center at the Medical University of South Carolina. The study is being done at the Medical University of South Carolina, but study recruitment is based state-wide, throughout South Carolina.

NCT ID: NCT03657511 Completed - Smoking Tobacco Clinical Trials

Tobacco Cessation Intervention

Start date: October 22, 2018
Phase: N/A
Study type: Interventional

This study is planned as an evaluation of a low cost, simple smoking cessation intervention. There is very little information about the effectiveness of a simple tobacco cessation strategy. Therefore, our objective is to obtain estimates of effectiveness that can be used to refine existing programs or to develop new ones.

NCT ID: NCT03651869 Completed - Smoking, Tobacco Clinical Trials

Effects of Nicotine in Tobacco Smokers

Start date: February 4, 2019
Phase: Phase 1
Study type: Interventional

This study will examine mechanisms linking Obsessive-Compulsive Disorder symptomatology to tobacco dependence.

NCT ID: NCT03645941 Completed - Smoking Cessation Clinical Trials

Connecting Alaska Native People to Quit Smoking

CAN Quit
Start date: December 13, 2019
Phase: N/A
Study type: Interventional

The prevalence of smoking among US adults is highest among American Indians and Alaska Native (AI/AN) persons; however, there are a lack of tobacco cessation interventions developed specific to this disparity group. Social media holds promise as a scalable intervention strategy to promote engagement in treatment and cessation outcomes for Alaska Native (AN) people. Researchers plan to develop and pilot test a culturally relevant, Facebook delivered intervention to promote smoking treatment uptake and cessation among AN smokers. The Facebook content will include a digital storytelling approach adapted from the effective Centers for Disease Control (CDC) Tips from Former Smokers educational mass media campaign. The project builds on the researcher team's longstanding tobacco control research partnership with the AN community and was informed by their understanding of cultural factors that can both impede and encourage cessation in this population. If the pilot intervention is successful, researchers will have a blueprint to conduct a large randomized controlled trial. The researchers long-term objective is to develop interventions for AN tobacco users that will ultimately reduce their risk of tobacco-caused disease and mortality.

NCT ID: NCT03612895 Completed - Smoking, Tobacco Clinical Trials

Proactive Population Health Strategy to Offer Tobacco Dependence Treatment to Smokers

Start date: April 2016
Phase: N/A
Study type: Interventional

Health care systems are key channels for delivering tobacco cessation treatment to the smokers in a population. A population-based approach could complement office-based care and offload busy clinicians. The project will conduct population-based proactive outreach to current smokers in a health care system's primary care practices and randomize smokers who respond to the outreach to 3 groups: 2 alternative evidence-based cessation resources or to usual care. Specific Aims: Aim 1: To determine the feasibility and reach of the program Aim 2a: To determine whether the 2 intervention arms combined increase the proportion of smokers who use tobacco cessation treatment over a 6-month follow-up compared to those randomized to usual clinical care. Aim 2b: To determine whether each of the two intervention arms increases the proportion of smokers who use tobacco cessation treatment over a 6-month follow-up, compared to those receiving usual clinical care.

NCT ID: NCT03611881 Completed - Smoking, Tobacco Clinical Trials

Assessing the Integration of Tobacco Cessation Treatment Into Lung Cancer Screening (LCS)

ScreenASSIST
Start date: April 8, 2019
Phase: Phase 4
Study type: Interventional

This randomized controlled trial seeks to evaluate the effectiveness of alternative strategies to integrate smoking cessation interventions into the delivery of low-dose CT (LDCT) lung cancer screening. Using a factorial design, current smokers who enroll will be randomly assigned to receive these interventions: (1) smoking cessation counseling support by telephone or videoconferencing (short duration vs. long duration); (2) nicotine patch treatment (NRT) (short vs.long duration); (3) counselor-facilitated referral (vs. no referral) to an online resource to connect smokers to a community-based social service resources.

NCT ID: NCT03597607 Completed - Quality of Life Clinical Trials

Evaluation of an Intensive Individualized Smoking Cessation Program Delivered by Pharmacists

Start date: September 18, 2018
Phase: N/A
Study type: Interventional

This study aims to look at the efficacy and impact of a pharmacist-led smoking cessation program. It will assess an intensive program and an abbreviated program, with the latter being evaluated for feasibility in community pharmacies. Participants will be in one of two groups: intensive or abbreviated. Smoking abstinence rates, self-efficacy and overall satisfaction will be compared. Additionally, a cost-effectiveness analysis will be executed to determine the feasibility of customized smoking cessation programs in community pharmacies across Newfoundland and Labrador.

NCT ID: NCT03553992 Completed - Smoking Cessation Clinical Trials

An Extended Facebook Intervention for Young Sexual and Gender Minority Smokers

POP-6
Start date: October 29, 2018
Phase: N/A
Study type: Interventional

The 2-year research plan will test the Extended Put It Out Project (POP-6) in a pilot randomized trial (N=168) compared to TSP-6, as well as comparing POP-6 and TSP-6 to the POP-3 and TSP-3 interventions from a previously-conducted trial. Participants will be young adults who smoke, identify as sexual or gender minorities (SGM), and use Facebook. Primary outcome will be biochemically verified 7-day abstinence from smoking at 3 and 6 months. Secondary outcomes will be a quit attempt (y/n), stage of change, and thoughts about tobacco abstinence at 3 and 6 months.

NCT ID: NCT03524482 Completed - Smoking Cessation Clinical Trials

Path2Quit Tobacco Intervention For African Americans

Start date: April 1, 2018
Phase: N/A
Study type: Interventional

The purpose of this research is to study a smoking cessation program for adult smokers in Northeast Ohio. The study will also look at how different people respond to the program. The study includes completing surveys and receiving text messages to help participants become tobacco free.

NCT ID: NCT03496077 Completed - Smoking Clinical Trials

Addictive Potential of LCCs in Dual Users

Start date: August 28, 2018
Phase: N/A
Study type: Interventional

This study is about whether or not little cigars and cigarillos cause or maintain addiction, and if flavors, such as fruit, make them more addictive. The purpose of this study is to understand the addiction potential of little cigars and cigarillos compared to cigarettes in young adults who smoke both products. This study will also look at the differences between men and women. In the rest of this form, little cigars or cigarillos will be referred to as LCCs.