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Skin Neoplasms clinical trials

View clinical trials related to Skin Neoplasms.

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NCT ID: NCT05702398 Not yet recruiting - Skin Cancer Clinical Trials

Pilot Trial of Supplemental Vitamin A and Nicotinamide

Start date: March 1, 2023
Phase: Early Phase 1
Study type: Interventional

The goal of this clinical trial is to assess the feasibility and safety of oral nicotinamide (NAM; a derivative of vitamin B3 [niacin]) and vitamin A in a high-risk population of kidney transplant recipients with a history of skin cancer to generate preliminary data for future cancer prevention clinical trials.

NCT ID: NCT05684692 Recruiting - Pain, Chronic Clinical Trials

Screening Trial for Pain Relief in Schwannomatosis (STARFISH)

Start date: August 31, 2023
Phase: Phase 2
Study type: Interventional

This is a placebo-controlled, multi-arm phase II platform screening trial designed to test the safety, pain responses, and pharmacodynamic activity of multiple experimental therapies simultaneously in participants with moderate-to-severe pain due to schwannomatosis (SWN). This Master Study is being conducted as a platform that may allow participants with pain associated with schwannomatosis to receive a novel intervention throughout this study. Embedded within the Master Study are individual drug sub-studies: - Investigational Drug Sub-Study A: Siltuximab - Investigation Drug Sub-Study B: Erenumab-Aooe

NCT ID: NCT05675709 Enrolling by invitation - Cutaneous Melanoma Clinical Trials

Enhancing Skin Cancer Early Detection and Treatment in Primary Care

Start date: April 25, 2023
Phase: N/A
Study type: Interventional

Skin cancer screening may help find melanoma sooner, when it may be easier to treat. If found early melanoma and other types of skin cancer may be curable. Multi-component education may be an effective method to help primary care physicians (PCPs) learn about skin cancer screening. This clinical trial examines whether a clinician-focused educational intervention can improve PCP's knowledge and clinical performance to identify and triage skin cancer. This intervention may increase the PCP's ability to diagnose, treat and/or triage early-stage melanoma.

NCT ID: NCT05661370 Completed - Melanoma (Skin) Clinical Trials

App Teaches Doctors to Diagnose Skin Cancer

Start date: November 15, 2021
Phase: N/A
Study type: Interventional

This study aimed to examine if self-paced learning with a novel digital patient-case-based educational platform can increase primary care physicians' diagnostic accuracy of malignant and benign skin lesions on both the level of benign/malignant and the diagnosis level. Secondarily the study aimed to investigate the time spent in reaching this change in proficiency.

NCT ID: NCT05648604 Recruiting - Melanoma Clinical Trials

Mentored Community Gardening for Individuals With Skin Cancer

H4H2-AZ
Start date: February 2, 2023
Phase: N/A
Study type: Interventional

The investigators will conduct a single-arm pilot feasibility trial of mentored community gardening for melanoma survivors integrating dosimeters and accelerometers. Harvest for Health Together Arizona (H4H2-AZ) is an evidence-based program adapted for arid desert gardening that also addresses sun safety through group workshops and peer education. The primary aim is to evaluate adherence to the intervention.

NCT ID: NCT05643755 Withdrawn - Skin Cancer Clinical Trials

Preoperative Image-based Education Effect on Postoperative Satisfaction of Patients Undergoing First-time Dermatologic Surgery

Start date: December 2025
Phase: N/A
Study type: Interventional

This research study aims to understand whether visual and written education on wound appearance can improve patients' experience and understanding of what their wound will look like following dermatologic surgery.

NCT ID: NCT05634252 Recruiting - Skin Cancer Clinical Trials

Undergraduate Skin Cancer Prevention Trial

RISE-UP
Start date: April 24, 2023
Phase: Phase 3
Study type: Interventional

The proposed study is a Multiphase Optimization Strategy (MOST) that uses factorial experiments to evaluate individual and combined effects of intervention components to improve intervention efficiency. The study team anticipates enrolling a total of 528 undergraduate students (>18 years) into the trial to identify intervention approaches that eliminate sunburn, and secondarily to motivate sun protection and discourage tanning. The study team will test personalized risk components: 1) UV Photo, 2) Action Plan, and 3) MC1R Testing. A full factorial experiment will be conducted to test which of the proposed components or their combinations eliminate sunburn over one year. The study team will also examine effects of the intervention on secondary outcomes. Study assessments will be completed at 4 time points: baseline, 1-month post-intervention, 4-months post-intervention, and 15-months post-intervention.

NCT ID: NCT05620290 Recruiting - Melanoma Clinical Trials

MRI-Guided Focused Ultrasound Radiosensitization for Patients With Malignant Melanoma and Non Melanoma Skin Cancer

Start date: June 15, 2022
Phase: Phase 1
Study type: Interventional

The objective of this study is to examine the safety profile and therapeutic efficacy of MRI-guided focused ultrasound microbubble therapy and radiotherapy in humans.

NCT ID: NCT05618912 Completed - Clinical trials for Patient Satisfaction

Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment

Start date: October 17, 2022
Phase: N/A
Study type: Interventional

Patients will be randomized either to receive standard daily dressing or hydrocolloid dressing using a randomization generator. After closing the wound with the sutures,the scar will be covered by a hydrocolloid dressing, which will be left in place for 7 days(Experimental) or the standard dressing (Control) that will be covered with petrolatum jelly and bandaging during this time period, which has to be re-applied daily. Patients and dermatologic surgeons will then complete surveys 7 days, 30 days, and 90 days after surgery to evaluate the cosmetic appearance of these scars.

NCT ID: NCT05602337 Not yet recruiting - Clinical trials for Melanoma and Other Malignant Neoplasms of Skin

A Prospective Multicenter Sample Collection Study Using Non-invasive Methods to Investigate Mutation Burden in Non-lesional Facial Skin of Patients With a Hx of Skin Cancer

Start date: November 15, 2022
Phase:
Study type: Observational

This is a prospective, multicenter, sample collection study using DermTech's non-invasive skin collection kits to evaluate the mutation burden of non-lesional facial skin from subjects with a documented history of numerous basal cell carcinomas, squamous cell carcinomas or melanomas compared to that of subjects with no history of skin cancer matched for age, sex and Fitzpatrick phototype.