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Skeletal Muscle Damage clinical trials

View clinical trials related to Skeletal Muscle Damage.

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NCT ID: NCT04795232 Completed - Clinical trials for Skeletal Muscle Damage

Recovery Kinetics Following Change of Direction Training

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

This study aims at investigating the recovery kinetics of skeletal muscle damage, neuromuscular fatigue and performance following a single change of direction (COD) training session in competitive soccer players. The impact of COD degrees will be also examined by comparing a 45o vs. 90o COD training session. Ten male soccer players will perform a COD45 [A single training session including 2x(10x ~27.6m) sprints with two 45o COD in each sprint], a COD90 [A single training session including 2x(10x ~21.2m) sprints with two 90o COD in each sprint] and a Control trial (No intervention included, only daily measurements) in randomized, repeated measures, crossover design. Assessments related to skeletal muscle damage, neuromuscular fatigue and performance will be performed prior to training session and daily for three consecutive days post-training, in each trial.

NCT ID: NCT04523675 Completed - Clinical trials for Skeletal Muscle Damage

NAC Supplementation and Soccer Specific Performance

Start date: April 2016
Phase: N/A
Study type: Interventional

In this investigation the investigators utilized NAC supplementation to boost GSH availability during an one-week-microcycle consisting of three soccer games, in order to test the hypotheses that: i) antioxidant supplementation may enhance the recovery of performance and physiological stress variables following multiple match-plays and ii) redox status perturbations are critical in regulating the inflammatory response and repair in skeletal muscle, following repetitive exercise-induced muscle injuries.

NCT ID: NCT03934762 Completed - Performance Clinical Trials

Aloe Vera Ointment Application and Skeletal Muscle Recovery

Start date: April 25, 2019
Phase: N/A
Study type: Interventional

Aloe vera, sometimes described as pharmaceutical aloe, is a flowering succulent plant with many therapeutic properties such as wound and burn wound healing, treatment of diabetes and reduction of blood lipid profile. These benefits have been primary attributed to its high content in polysaccharides, anthraquinones and lectins. However, aloe vera includes more than 200 ingredients and nutrients (i.e. vitamins, saponins, amino acids, anthraquinones, minerals and trace-elements, salicylic acid, saccharides, lignin, enzymes, sterols) the combination of which offers more powerful effects and health-related benefits compared to each one of them separately. Thus, based on the ingredients and nutrients included, it has been proposed that aloe vera may also offer anti-inflammatory, antioxidative, analgesic and anabolic benefits. Exercise training, especially when it is unaccustomed or characterized by increased intensity, results in skeletal muscle microtrauma accompanied by elevated plasma levels of Creatine Kinase (CK), increased sensation of muscle soreness (DOMS), reduced force generating capacity and marked declines in speed and agility. Both anti-inflammatory and antioxidative mechanisms in skeletal muscle are crucial for the termination of inflammatory response and muscle healing process following exercise-induced aseptic muscle injury and inflammation. Although, it has been proposed that ale vera may elicit anti-inflammatory and antioxidative activity, its effectiveness in alleviating exercise-induced skeletal muscle injury and its symptoms, has not been investigated yet. Therefore, the aim of the present pilot study is to examine the effect of transdermal aloe veral delivery on skeletal muscle damage symptoms following an intense eccentric exercise protocol.

NCT ID: NCT03753321 Completed - Muscle Damage Clinical Trials

Whey and Soy Protein Supplementation in Football Players

Start date: November 8, 2018
Phase: N/A
Study type: Interventional

In a constant effort to find ways to make a quicker recovery between demanding workouts and football matches, this study is the first to investigate the benefits of protein supplementation, and compares two types of proteins, an animal-derived (whey) and a plant-derived (soy) protein, after an exercise-induced muscle injury caused by a speed endurance training protocol. Soy protein could be a cheaper and more environment-friendly alternative for athletes involved in high-velocity strength training.

NCT ID: NCT03348267 Completed - Clinical trials for Skeletal Muscle Damage

Protein Supplementation and Muscle Recovery in Football

PRO-FOOTBALL
Start date: May 1, 2016
Phase: N/A
Study type: Interventional

Soccer is an intermittent sport including a high number of powerful actions such as accelerations, decelerations, changes of direction, jumps and impacts that incorporate a strong eccentric component and may therefore lead to skeletal muscle damage. Indeed, match activity is associated with the onset of muscle damage and an acute inflammatory response that result in attenuated performance for as long as 1 to 3 days. In competitive soccer though, multiple matches are performed within a small-time frame resulting in inadequate muscle recovery and reduced field performance. Supplementation with milk proteins following intense exercise protocols has been shown to stimulate protein synthesis and facilitate muscle recovery. Thus, the aim of the present investigation is to examine the effects of milk protein supplementation on muscle recovery and soccer-specific performance during an in-season microcycle with two matches performed three days apart.

NCT ID: NCT02930031 Completed - Clinical trials for Skeletal Muscle Damage

Redox Status and Immune Function

Start date: January 2015
Phase: N/A
Study type: Interventional

In this investigation the investigators utilized N-acetylcysteine (NAC) supplementation to enhance reduced glutathione (GSH) stores during an 8-day recovery period from a strenuous eccentric exercise protocol in order to test the hypotheses: i) redox status perturbations in skeletal muscle are pivotal for the immune responses and ii) antioxidant supplementation may alter immune cell responses following exercise-induced muscle microtrauma.

NCT ID: NCT02816411 Completed - Clinical trials for Skeletal Muscle Damage

Protein Supplementation and Skeletal Muscle Healing Process

Start date: May 2014
Phase: N/A
Study type: Interventional

In this study the investigators utilized protein supplementation over an 8-day period following eccentric exercise-induced muscle damage in order to test the initial hypotheses : i) protein supplementation after exercise-induced muscle injury affects exercise-induced aseptic inflammation and muscle performance.

NCT ID: NCT01778309 Completed - Clinical trials for Skeletal Muscle Damage

NAC Supplementation and Skeletal Muscle Performance

Start date: January 2010
Phase: N/A
Study type: Interventional

In this investigation the investigators utilized NAC administration to foster GSH availability during an 8-day period following eccentric exercise-induced muscle damage in order to test our hypotheses: i) antioxidant supplementation does not disturb performance and adaptations induced by exercise-induced muscle injury and ii) redox status perturbations in skeletal muscle are pivotal for the regulation of muscle' inflammatory response and repair.