Clinical Trials Logo
  1. Home
  2. Sjogren's Syndrome
  3. NCT03411850
  4. Details
NCT03411850 Clinical Trial

Sjogrens Syndrome Measured by Ultrasound

Sjogren's Syndrome Clinical Trial

Official title:
Disease Modification in Sjogrens Syndrome Measured by Ultrasound: A Pilot Study

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT03411850
Other study ID # BMS IM101-560
Secondary ID
Status Active, not recruiting
Phase Phase 2
First received
Last updated
Start date May 2016
Est. completion date December 2021

Study information
Verified date May 2021
Source Arthritis & Rheumatism Associates, P.C.
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Ultrasound study focused on salivary gland outcomes in Sjogren's subjects

Description:

A 32 week ultrasound study for subject diagnosed with Sjogren's Syndrome. Subjects will receive Orencia (Abatacept) as intervention therapy during this trial.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 20
Est. completion date December 2021
Est. primary completion date May 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 65 Years
Eligibility Inclusion Criteria: - Subjects diagnosed with Sjogren's Syndrome Exclusion Criteria: - Subjects previously diagnosed with Sarcoidsis - Subjects with positive for Hepatitis B, Hepatitis C, HIV - Subjects diagnosed with Cancer within 5 years of screening

Study Design

Related Conditions & MeSH terms

Intervention

Biological:
• Orencia
FDA approved biologic
Other:
• Placebo

Locations
Country Name City State
United States The Center for Rheumatology and Bone Research a division of Arthritis and Rheumatism Associates, P.C. Wheaton Maryland

Sponsors (2)
Lead Sponsor Collaborator
Arthritis & Rheumatism Associates, P.C. Bristol-Myers Squibb

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Salivary gland changes Salivary gland changes detected by ultrasound imaging with elastography 32 weeks
See also
  Status Clinical Trial Phase
Completed NCT03248518 - Lessening the Impact of Fatigue in Inflammatory Rheumatic Diseases N/A
Completed NCT04968912 - A Study of Nipocalimab in Adults With Primary Sjogren's Syndrome (pSS) Phase 2
Completed NCT03203382 - Corneal Nerve Structure in Sjogren's
Completed NCT00809003 - Assessment of Inflammatory and Functional Changes in the Ocular Surface Associated With Dry Eye Disease N/A
Completed NCT00023491 - Potential of Transplanted Stem Cells to Mature Into Salivary Gland and Cheek Cells N/A
Completed NCT05005806 - Fish Oil (Omega 3 ) in Sjogren's Syndrome Phase 2/Phase 3
Enrolling by invitation NCT03436576 - Efficacy of Two Concentrations of Autologous Serum for the Treatment of Severe Dry Eye Phase 3
Terminated NCT04143841 - Viveye Ocular Magnetic Neurostimulation System (OMNS) for the Management of Severe Dry Eye Disease N/A
Completed NCT03611283 - Topical Management of Xerostomia With Dry Mouth Products N/A
Recruiting NCT06104124 - A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity Phase 3
Recruiting NCT05115487 - Evaluation of Hand Functions in Newly Diagnosed Primary Sjögren's Syndrome
Recruiting NCT06437652 - An AI Algorithm for Lymphocyte Focus Score of Minor Salivary Gland Biopsy Samples for Diagnosing Sjogren's Syndrome
Recruiting NCT05383677 - Anifrolumab Treatment for 24 Weeks in Patients With Primary Sjögren's Syndrome Phase 2
Not yet recruiting NCT03938207 - Dry Eye Syndrome, Healthy Control, Sjögren's Syndrome and Other Inflammation Disease in Taiwan Biobank
Completed NCT04239521 - The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata
Completed NCT04546542 - Hydroxychloroquine Blood Levels in Primary Sjögren Syndrome Patients
Recruiting NCT05085431 - A Study of CD19/BCMA Chimeric Antigen Receptor T Cells Therapy for Patients With Refractory Sjogren's Syndrome Early Phase 1
Completed NCT00565526 - Evaluation of the Role of the Autonomic Nervous System in Sj(SqrRoot)(Delta)Gren s Syndrome
Completed NCT01369589 - An Evaluation of the Impact of a Single Dose of P-552 on Oral Mucosal Wetness Phase 1/Phase 2
Completed NCT00001953 - The Functioning of Immune and Hormonal Systems in Patients With Sjogren's Syndrome and in Healthy Volunteers N/A