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Sinusitis clinical trials

View clinical trials related to Sinusitis.

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NCT ID: NCT01623050 Completed - Sinusitis Clinical Trials

Safety and Performance of the SinuSys Dilation System for Dilation of the Maxillary Sinus Ostium

Start date: April 2012
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess safety and performance of the SinuSys Dilation System for dilation of the maxillary sinus ostium.

NCT ID: NCT01612780 Completed - Sinusitis Clinical Trials

Trans-Nasal Maxillary Multi-Sinus Balloon Dilation Study

Start date: April 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to show clinically meaningful improvement in symptom severity after transnasal balloon dilation of the maxillary sinus outflow tract with or without balloon dilation of the frontal or sphenoid sinuses.

NCT ID: NCT01608308 Completed - Chronic Sinusitis Clinical Trials

Intraoperative and Post-operative Analgesic Effect of IV Acetaminophen for Sinus Surgery

IVAPAP
Start date: July 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the use of IV acetaminophen (Ofirmev) as a and safe and efficacious agent in reducing post-operative pain; we hypothesize that its use will reduce post-operative pain when compared to a control group using the visual analogue score (VAS) analog pain scoring system.

NCT ID: NCT01575223 Completed - Clinical trials for Chronic Rhinosinusitis

Saline Irrigation After Surgery in Patients With Chronic Sinusitis

HVSI
Start date: March 2012
Phase: Phase 4
Study type: Interventional

Purpose: To determine if high volume saline nasal irrigation (HVSI), (NeilMed® Sinus Rinseā„¢) offers a benefit over low volume saline irrigation (LVSI), (Salinex®) in the early post-operative management in patients with chronic rhino sinusitis.

NCT ID: NCT01564849 Recruiting - Sinusitis Clinical Trials

The Clinical Efficacy of Topical Nasal Pomegranate Fruit Extract for Patients With Chronic Rhinosinusitis

Start date: April 2012
Phase: N/A
Study type: Observational

An explosion of interest in the numerous therapeutic properties of Punica granatum over the last decade has led to numerous in vitro, animal, and clinical trials. Pomegranate is a potent antioxidant, superior to red wine and equal to or better than green tea. In addition, anticarcinogenic and anti-inflammatory properties suggest its possible use as a therapy or adjunct for prevention and treatment of several types of cancer and cardiovascular disease. Because of pomegranate's antimicrobial properties, it may aid in preventing infection by dental pathogens, pathogenic E. coli O157:H7, and antibiotic-resistant organisms such as methicillin-resistant Staphylococcus aureus (MRSA) Pomegranate's effect on bacterial pathogens has only been tested in vitro, however, necessitating human trials to refute or substantiate any clinical effect. The possibility that pomegranate extracts may also have an effect on several other disease processes, such as Alzheimer's and obesity, underscores the need for more clinical research. Currently, numerous clinical trials are in progress exploring the therapeutic potential of pomegranate extracts. Aim The investigators want to evaluate the effect of Punica granatum components on Chronic sinusitis, nasal polyps and chronic rhinitis.

NCT ID: NCT01553110 Completed - Allergic Rhinitis Clinical Trials

An Observational Study to Evaluate The Relationship of Nasal Mucus Properties and Symptoms

Start date: March 2012
Phase:
Study type: Observational

This is a study to learn more about the common cold from studying the nasal secretions produced during a cold or episode of allergic rhinitis.

NCT ID: NCT01553006 Recruiting - Rhinosinusitis Clinical Trials

Study of Cefditoren Pivoxil in Treatment of Childhood With Acute Rhinosinusitis

RS
Start date: January 2012
Phase: Phase 4
Study type: Interventional

Cefditoren pivoxil has been used in rhinosinusitis treatment. However, little is known about the efficacy of this drug at low and high doses.

NCT ID: NCT01525862 Completed - Chronic Sinusitis Clinical Trials

XprESS Maxillary Balloon Dilation Study

Start date: December 2011
Phase: N/A
Study type: Interventional

A prospective, single-arm, post approval pilot study.

NCT ID: NCT01492868 Completed - Sinusitis Clinical Trials

Sinusitis in Children and the Nasopharyngeal Microbiome

Start date: January 2012
Phase:
Study type: Observational

The purpose of this study is to investigate the relationship between viral infections of the upper respiratory tract, perturbations of the nasopharyngeal microbiome in children, and the risk of acute bacterial sinusitis over a one year period. The investigators will determine the incidence of acute bacterial sinusitis post viral upper respiratory infection and identify the viral antecedent infections and other risk factors which predispose to infection and ultimately design strategies to reduce the burden of disease and antimicrobial resistance.

NCT ID: NCT01485484 Completed - Sinusitis Clinical Trials

Development and Validation of a NIRS-based Sinusitis Screening

Start date: July 28, 2011
Phase:
Study type: Observational

The research at University of California Irvine, Beckman laser institute and Praxis Biosciences Incorporation, develope near-infrared trans-illumination methods. The optical imaging tool that can determine acute sinusitis and the response to treatment therapy.