Simethicone Clinical Trial
Official title:
Simethicone and Gynecological Laparoscopies: Does it Improve Operative Field and Postoperative Pain?
Simethicone is an oral anti-foaming agent that reduces bloating, abdominal discomfort, and
abdominal pain by promoting the clearance of excessive gas along the gastrointestinal tract.
The investigators objective is to evaluate the efficacy and safety of preoperative oral
simethicone for bowel preparation in gynecological laparoscopies.
Introduction: Simethicone is an oral antifoaming agent that reduces bloating, abdominal
discomfort, and abdominal pain by promoting the clearance of excessive gas along the
gastrointestinal tract.
Objective: to evaluate the efficacy and safety of preoperative oral simethicone for bowel
preparation in gynecological laparoscopies.
Methods: 100 infertile women will be scheduled for laparoscopy, patients randomized to
receive either Simethicone (Group I) or placebo tablets (Group II). The primary outcome
measure will be the overall exposure of the surgical field and pain scoring. Assessment of
the overall exposure of the surgical field was done using a five-point scale (poor,
sufficient, medium, good, and excellent). Visual analog score (VAS) will be used for
assessment of postoperative pain and verbal analog scoring was used for assessment of
patient satisfaction.
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Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Treatment