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A Voxelotor for Sickle Cell Anemia Patients at Highest Risk for Progression of Chronic Kidney Disease

Sickle Cell Disease Clinical Trial

Official title:
A Pilot Study of Voxelotor for Sickle Cell Anemia Patients at Highest Risk for Progression of Chronic Kidney Disease

Clinical Trial Summary

This study is a single center, prospective exploratory pilot study of Sickle Cell Anemia (SCA) participants. The study will enroll patients with early stages of sickle cell nephropathy (Chronic Kidney Disease (CKD) stage 1 or 2) who are at the highest risk of CKD progression (presence of both hemoglobinuria and urine albumin concentration ≥ 30 mg/g creatinin

Clinical Trial Description

This study is a single center, prospective exploratory pilot study of Sickle Cell Anemia (SCA) participants, age ≥18 years, with SCA. The study will enroll patients with early stages of sickle cell nephropathy (Chronic Kidney Disease (CKD) stage 1 or 2) who are at the highest risk of CKD progression (presence of both hemoglobinuria and urine albumin concentration ≥ 30 mg/g creatinin ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04335721
Study type Interventional
Source University of Illinois at Chicago
Contact Santosh Saraf, MD
Phone 312-996-5680
Email ssaraf@uic.edu)
Status Recruiting
Phase Phase 1/Phase 2
Start date March 16, 2021
Completion date August 2024
View Details
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