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Haploidentical Hematopoietic Stem Cell Transplantation (HSCT) for Patients With Severe Sickle Cell Disease

Sickle Cell Disease Clinical Trial

Official title:
Hematopoietic Stem Cell Transplantation for Patients With Severe Sickle Cell Disease Using Myeloablative Conditioning and αβ+ T-cell Depleted Hematopoietic Stem Cells From Partially Matched Familial Donors

Clinical Trial Summary

The purpose of this study is to develop a safe and curative stem cell transplant approach to treating sickle cell disease by assessing the safety of haploidentical hematopoietic stem cell transplantation using αβ+ T-cell depletion for children and adolescents with severe sickle cell disease (SCD).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04207320
Study type Interventional
Source University of Chicago
Contact Rebecca Puplava
Phone 773-702-2879
Email rpuplava@peds.bsd.uchicago.edu
Status Recruiting
Phase N/A
Start date April 7, 2020
Completion date November 2027
View Details
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