Sickle Cell Disease Clinical Trial
Official title:
Patient Centered Outcomes Research Institute (PCORI) ESCAPED Study: Comparison of Patient Centered Outcomes for People With SCD in the Acute Care Setting
The Emergency Department has been the standard location where patients with Sickle Cell
Disease (SCD) go to seek care for the treatment of acute painful events. Vaso- Occlusive
Crisis (VOC) is the most common complication of SCD,
The purpose of this study is to compare patient centered outcomes for patients being treated
for an uncomplicated VOC in Infusion Centers (IC) and Emergency Departments (ED) in four
locations around the United States.
Emergency Department care is marked by long delays, lack of efficacy, and conflict. A
sub-specialty Infusion Center staffed by expert clinicians and delivering individualized care
can improve care quality while reducing costs. The study will examine whether care provided
in an Infusion Center (IC) is more patient centered and efficient than care provided in an
Emergency Department (ED) for adults with Sickle Cell Disease (SCD) and uncomplicated
Vaso-Occlusive Crisis (VOC).
Sites will prospectively enroll patients in VOC seen in participating centers from either the
EDs or the ICs. Specific data from the acute visits (e.g. Times of arrival, time to first
dose of analgesic, etc) will be captured. This study will compare: pain management,
disposition of subjects (home or admission) and patient experiences of care delivery in both
settings. Subjects will complete surveys/questionnaires to asses subjects' experiences in the
setting where care was provided.
The four sites to participate in the study are Baltimore, Maryland (Johns Hopkins Hospital),
Cleveland, Ohio (Cleveland Medical Center), Milwaukee, Wisconsin (Medical College of
Wisconsin), and Baton Rouge, Louisiana (Our Lady of the Lake Hospital). A maximum of 500
subjects will participate in the study. Participants will be enrolled for 18 months.
;
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