Study of Blood Platelets in Sickle Cell Disease

Sickle Cell Disease Clinical Trial

Official title:

Studies of Large Platelets in Patients With Sickle Cell Disease

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT00226083
• Other study ID #: RUH IRB # AST-0565-0805
• Status: Withdrawn
• Phase: N/A
• First received: September 22, 2005
• Last updated: June 5, 2015
• Start date: August 2005
• Est. completion date: September 2007

Study information

• Verified date: June 2015
• Source: Rockefeller University
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Food and Drug Administration
• Study type: Observational

Clinical Trial Summary

We are studying if sickle cell disease blood platelets are larger than normal and how they may cause obstruction of blood vessels. We are also trying to study the reasons why large platelets are found in patients with sickle cell disease.

Description:

Research volunteers are seen in the Outpatient Research Center by the Principal Investigator or another physician. A detailed history is obtained, a physical examination is performed, and blood (usually 4 tablespoons) is obtained for additional tests. The research volunteer's previous medical records will be requested. Upto 5 additional blood samples may be obtained in a subgroup of patients.

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Est. completion date: September 2007
• Est. primary completion date: September 2007
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 7 Years and older

Eligibility

Inclusion Criteria:

• Adults and children > 7 years of age with sickle cell disease (Hb SS) who are not taking hydroxyurea and are not receiving routine blood transfusion therapy.

Exclusion Criteria:

• Current hydroxyurea therapy or,

• Hydroxyurea use within the past 3 months

• Blood transfusion or exchange transfusion within the past 3 months

• Current treatment with aspirin or clopidogrel

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

• Anemia, Sickle Cell
• Sickle Cell Disease

Locations

Country	Name	City	State
United States	Rockefeller University Hospital	New York	New York

Sponsors (3)

Lead Sponsor	Collaborator
Rockefeller University	Icahn School of Medicine at Mount Sinai, Schneider Children's Hospital of North Shore

Country where clinical trial is conducted

United States,