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Clinical Trial Summary

This study is being conducted to determine the relationship between early childhood exposures, such as Adverse Childhood Experiences, Social Determinants of Health and nutrition/breastfeeding, among children with sickle cell disease, and behavioral interventions aimed to reshape psychological resilience and lifestyle factors towards positive health outcomes.


Clinical Trial Description

During year 3 of the award period, 20 mother-infant dyads will be randomly assigned to either a community-based breastfeeding support group or observation. Acceptability to enrollment, intervention adherence for at least 6 months and preliminary effectiveness will be captured. Biomarkers of inflammation, development of asthma and incidences of pain and/or acute chest syndrome will be compared among the intervention and control groups. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05377372
Study type Interventional
Source University of Alabama at Birmingham
Contact Brandi M Pernell, DNP, MSPH
Phone 2058640238
Email brandimcclain@uabmc.edu
Status Not yet recruiting
Phase N/A
Start date May 1, 2025
Completion date December 31, 2027

See also
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