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Clinical Trial Summary

This work aims to:

1. Investigate and correlate Sexual Dysfunction in relapsing-remitting Multiple Sclerosis patients with specific focus on

1. Specific neurologic deficit.

2. Depressive symptoms.

3. Comorbid factors.

4. Fatigue symptoms.

2. To investigate the impact of Sexual dysfunction on Sexual Quality of Life (SQoL).

3. To search for possible gender difference.


Clinical Trial Description

The present study is a cross sectional study on 120 MS adolescent patients meeting the McDonald's criteria; 60 male cases and 60 female cases recruited from Mansoura University Hospitals, Egypt.

All patients were subjected to the following:

1. Clinical Evaluation:

1. Thorough neurological examination.

2. Cognitive functions by Minimental State Examination (MMSE).

e. Expanded Disability Severity Scale (EDSS).

2. Neurophysiological Evaluation:

a. Visual Evoked Potential (VEP).

3. Imaging Evaluation:

a. Conventional MRI.

4. Cerebrospinal Fluid (CSF):

5. Sexual dysfunction measure: through the international index of erectile function (IIEF), female sexual function questionnaire (SFQ) and the sexual Quality of life male and female version (SQoL) (American Psychiatric Association, 1994).

6. Depressive symptoms assessment through The BDI (The Beck Depression Inventory) which is the most common instrument measuring the severity of depression.

7. Fatigue symptoms were evaluated through fatigue subscale of Multiple Sclerosis Quality of Life-54(MSQOL-54). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04157283
Study type Observational
Source Mansoura University Hospital
Contact Esmael M Ahmed, MD
Phone 00201000372787
Email deltaneuro@yahoo.com
Status Recruiting
Phase
Start date November 5, 2019
Completion date June 1, 2020

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