Sepsis Clinical Trial
Official title:
Predictive Value of Procalcitonin for Bacteremia in the ICU
Association between plasma procalcitonin levels and positive blood cultures in critical illness patients in the ICU.
Rationale: Association of procalcitonin levels and blood cultures in critical illness patients on the ICU. Objective: Procalcitonin is an acute phase protein. As part of the acute phase response, procalcitonin is produced during sepsis. Previous research shows that procalcitonin is a biomarker for bloodstream infection. However, there is still little known about the value of procalcitonin in diagnostics for micro-organism underlying a sepsis in ICU patients. In modern practice, blood cultures are taken when a patient is septic to determine the responsible micro-organism. When procalcitonin is a predictive value for bacteremia in the ICU, the number of blood cultures can be reduced. Study design: An observational cohort study intervention: for each patient in the ICU blood cultures were taken, the procalcitonin level was determined. During 6 months 150 patients will be included. Main study parameters/endpoints: this study will examine the predictive value of procalcitonin in blood cultures on the ICU. ;
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