Sepsis Clinical Trial - Serum Proteomics Analysis for Sepsis

Status Recruiting

Clinical Trial Summary

Serum proteomics is a very useful tool to identify various disease. The purpose of the present study was to find differential proteins among patient with normal, SIRS, sepsis, severe sepsis, death and to screen potential biomarkers for their dynamic changes. Serum proteins were identified by iTRAQ labeling and LC-MS/MS. The bioinformatics analysis was performed with the Mascot software and the International Protein Index (IPI) and the Gene Ontology (GO) Database and KEGG pathway Database. The differentially expressed proteins were verified by Western blot by another sample collected from clinical.

Clinical Trial Description

n/a

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01493466
Study type	Observational
Source	Chinese PLA General Hospital
Contact	Longxiang Su, MD
Phone	+86 15620952878
Email	slx77@163.com
Status	Recruiting
Phase	N/A
Start date	May 2010
Completion date	March 2012

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