The Effect of Intensive Insulin Therapy in the Surgical Critical Care Unit

Sepsis Clinical Trial

Official title: No Outcome Benefit for the Use of Intensive Insulin Therapy in the Critically Ill General and Vascular Surgical Patient. A Randomized Prospective Trial.

Status Completed

Clinical Trial Summary

We sought to determine if there is a benefit to using an insulin drip to control hyperglycemia in the surgical critical care unit for patients who undergo general and vascular surgery.

Clinical Trial Description

While evidence exists for using tight glycemic control in the critically ill cardiac surgical patient, other patient populations have yet to be studied. We performed a prospective randomized trial for using intensive insulin therapy in the general and vascular critically ill surgical patient population. We will compare tight glycemic control versus conventional glycemic control to determine if there is a benefit to the normalization of blood glucose levels in this patient population ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Renal Failure
• Respiratory Failure
• Respiratory Insufficiency
• Sepsis
• Surgical Site Infection
• Surgical Wound Infection

• NCT number: NCT00282594
• Study type: Interventional
• Source: Genesys
• Status: Completed
• Phase: N/A
• Start date: July 2003
• Completion date: October 2005