Clinical Trials Logo
  1. Home
  2. Sentinel Lymph Node
  3. NCT03123042

Feasibility Study of Sentinel Navigation Surgery After Non-curative Endoscopic Resection — SENORITA2  

Sentinel Lymph Node Clinical Trial

Official title:
Feasibility Study of Sentinel Navigation Surgery in Early Gastric Cancer Patients After Non-curative Endoscopic Resection

Clinical Trial Summary

Purpose: To prove the feasibility of sentinel node navigation surgery (SNNS) in early gastric cancer patients with the risk of lymph node metastasis after endoscopic resection and preparation of multicenter phase 3 trial of stomach preserving surgery in these patients. Contents: The number of enrollment is 247 patients. The patients underwent endoscopic resection for early gastric cancer, and the tumor was defined to be out of indication for endoscopic resection pathologically. So, additional gastrectomy is recommended for them. The investigators will enroll patients who agree this study. After general anesthesia, Tc99m-Phytate with indocyanine green will be injected with endoscopy. Then sentinel basin will be detected using gamma probe and laparoscopic basin dissection will be done. Sentinel lymph node will be identify in back table dissection, and patients will undergo conventional gastrectomy. Detection rate and false negative rate will be evaluated by pathological review.

Clinical Trial Description

Sentinel basin dissection method 1. endoscopic tracer injection after general anesthesia 2. Tracer : Tc99m-phytate 3cc and indocyanine green 3cc mix --> Injection of the probe (1cc/site, 4 sites) around endoscopic submucosal dissection ulcer scar 3. Sentinel basin identification with laparoscopic probe 4. Dissection of the sentinel basin 5. Sentinel node dissection at back table 6. Conventional laparoscopic gastrectomy ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03123042
Study type Interventional
Source National Cancer Center, Korea
Contact Bang Wool Eom, MD, PhD
Phone 82-31-920-1689
Email kneeling79@ncc.re.kr
Status Recruiting
Phase N/A
Start date March 20, 2017
Completion date December 31, 2024
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05437380 - Peritumoral Microbubbles and CEUS for SLN Detection and Biopsy in HNSCC N/A
Active, not recruiting NCT04303715 - No Axillary sUrgical Treatment In Clinically Lymph Node Negative Patients After UltraSonography N/A
Completed NCT05498051 - Fluorescent Sentinel Lymph Node Identification in Colon Carcinoma Using Submucosal Bevacizumab-800CW. N/A
Active, not recruiting NCT06169787 - Sentinel Lymph Nodes Biopsy in Cervical Cancer
Completed NCT03294330 - SPY-X: A Study to Assess the Feasibility of Using SPY Alone for Sentinel Node Localization for Melanoma or Breast Cancer Phase 3
Not yet recruiting NCT04930692 - A Prospective Single-center Cohort Study "Preoperative Identification of Sentinel Lymph Nodes Using Contrast-enhanced CT Lymphography in Breast Cancer Patients" N/A
Recruiting NCT03749707 - HPV in Sentinel Lymph Nodes N/A
Completed NCT03899441 - Multimedia Aid Gynecologic Counseling and Consent N/A
Recruiting NCT04826211 - Axillary Staging in Node Positive Breast Cancer Patients Receiving PST. SNB vs PET/MRI N/A
Not yet recruiting NCT06130241 - Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Initially Node Positive Breast Cancer Patients, Could it Omit Axillary Dissection ? N/A
Recruiting NCT04664582 - Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and Neck N/A
Withdrawn NCT04487912 - Dynamics and Tracer Distribution of Tilmanocept in Early Stage Breast Cancer Phase 4
Completed NCT03563781 - SEntine Lymph Node in earLY Ovarian Cancer (SELLY) N/A
Recruiting NCT05623280 - Artificial Intelligence Analysis of Fluorescence Image to Intraoperatively Detect Metastatic Sentinel Lymph Node.
Active, not recruiting NCT05359783 - Sentinel Node Localization and Staging With Low Dose Superparamagnetic Iron Oxide Phase 1/Phase 2
Not yet recruiting NCT04568941 - Comparison Study of Different Tumor Biopsy Method for Sentinel Lymph Node Biopsy in Breast Cancer N/A
Completed NCT03606616 - Prospective Feasibility Study Applying the ACOSOG Z0011 Criteria to Chinese Patients
Recruiting NCT02982148 - Methylene Blue Intradermal Injection for Sentinel Lymph Node Biopsy for Breast Cancer Patients Phase 4
Recruiting NCT06161428 - Optical Guided Sentinel Node Biopsy for Staging of Vulvar Cancer
Completed NCT03900104 - Cervical and Endometrial Injection for Sentinel Lymph Node Detection in Endometrial Cancer N/A