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Seizures clinical trials

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NCT ID: NCT00236756 Completed - Epilepsy Clinical Trials

A Study of the Efficacy and Safety of Topiramate as an add-on Therapy in the Treatment of Epilepsy Patients With Lennox-Gastaut Syndrome

Start date: August 1993
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effectiveness and safety of topiramate as add-on therapy in the treatment of epilepsy patients with Lennox-Gastaut syndrome, a severe form of epilepsy in which there are mixed types of seizures.

NCT ID: NCT00236743 Completed - Epilepsy Clinical Trials

A Study of the Effectiveness and Safety of Topiramate in the Treatment of Children With Epilepsy

Start date: June 1994
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and effectiveness of oral topiramate as add-on therapy in children with uncontrolled partial onset seizures who are taking one or two standard anti-epileptic drugs.

NCT ID: NCT00236730 Completed - Epilepsy Clinical Trials

A Study of the Efficacy and Safety of Topiramate in the Treatment of Patients With Difficult to Control Epilepsy

Start date: June 1988
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate the effectiveness and safety of topiramate as add-on therapy in patients with difficult to control partial onset seizures who are taking one or two standard anti-epileptic drugs.

NCT ID: NCT00236717 Completed - Epilepsy Clinical Trials

A Study of the Effectiveness and Safety of Topiramate Compared With a Standard Therapy in Patients Newly Diagnosed With Epilepsy

Start date: September 1997
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the effectiveness and safety of topiramate to standard antiepileptic drugs in children and adults with newly diagnosed epilepsy.

NCT ID: NCT00236704 Completed - Epilepsy Clinical Trials

A Study of the Efficacy and Safety of Topiramate as "Add on" Treatment in Epilepsy Patients With Primary Generalized Tonic-clonic Seizures

Start date: March 1994
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effectiveness and safety of topiramate as an add-on therapy in epilepsy patients with uncontrolled primary generalized tonic-clonic seizures, who are taking 1 or 2 standard antiepileptic drugs.

NCT ID: NCT00236691 Completed - Epilepsy Clinical Trials

A Study of the Efficacy and Safety of Topiramate as add-on Therapy in the Treatment of Epilepsy Patients With Difficult to Treat, Partial-onset Seizures.

Start date: July 1988
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of topiramate as add-on therapy in patients with difficult to control partial onset seizures who are taking one or two standard antiepileptic drugs.

NCT ID: NCT00236418 Completed - Epilepsy Clinical Trials

A Study of the Efficacy and Safety of Topiramate in Epilepsy Patients With Primary Generalized Tonic-clonic Seizures

Start date: December 1994
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of topiramate as an add-on therapy in epilepsy patients with uncontrolled primary generalized tonic-clonic seizures, who are taking 1 or 2 standard antiepileptic drugs.

NCT ID: NCT00235755 Completed - Clinical trials for Partial-Onset Seizures

Retigabine Efficacy and Safety Trial for Partial Onset Refractory Seizures in Epilepsy

RESTORE2
Start date: December 2005
Phase: Phase 3
Study type: Interventional

This Phase 3 study is being conducted to evaluate the efficacy and safety of retigabine dosed at 900 mg/day and 600 mg/day, in three equally divided doses, compared with placebo in patients with epilepsy who are receiving up to three established antiepileptic drugs (AEDs).

NCT ID: NCT00233012 Completed - Seizures Clinical Trials

A Study of the Pharmacokinetics, Safety and Tolerability of Topiramate in Infants (Age 1-24 Months) With Refractory Partial-onset Seizures

Start date: June 2005
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the pharmacokinetics safety and tolerability of topiramate in infants aged 1-24 months with refractory partial-onset seizures. Topiramate is an antiepileptic drug approved for use in adult and pediatric patients (aged 2 to 16 years) with refractory partial onset seizures (POS) with or without secondarily generalized seizures, primary generalized tonic clonic seizures, or Lennox-Gastaut syndrome (LGS).

NCT ID: NCT00232596 Completed - Clinical trials for Partial-Onset Seizures

Retigabine (Adjunctive Therapy) Efficacy and Safety Study for Partial Onset Refractory Seizures in Epilepsy

RESTORE1
Start date: September 2005
Phase: Phase 3
Study type: Interventional

This Phase 3 study is being conducted to evaluate the efficacy and safety of retigabine dosed at 1200 mg/day, in three equally divided doses, compared with placebo in patients with epilepsy who are receiving up to three established antiepileptic drugs (AEDs).