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Seizures clinical trials

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NCT ID: NCT00864006 Completed - Seizures Clinical Trials

Bioequivalence Study of Divalproex Sodium 125 MG Delayed Release Tablets Under Fasting Conditions

Start date: October 2006
Phase: Phase 1
Study type: Interventional

The purpose of this study is to demonstrate the bioequivalence of divalproex sodium 125 MG delayed release tablets.

NCT ID: NCT00849212 Completed - Clinical trials for Refractory Partial Seizures

An add-on Study of E2007 in Patients With Refractory Partial Seizures Uncontrolled With Other Anti-epileptic Drugs (AEDs)

Start date: April 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to explore the maximum tolerated dose of E2007 in Japanese patients with refractory partial seizures which are uncontrolled with other anti-epileptic drugs (AEDs). Thirty patients will receive E2007 (dose escalating to the maximum of 12 mg per day). The dose of E2007 will be adjusted during 6 weeks. Subsequently, the dose will be fixed and maintained during 4 weeks.

NCT ID: NCT00835627 Completed - Depression Clinical Trials

Treatment Trial for Psychogenic Nonepileptic Seizures

NEST-T_1
Start date: September 2008
Phase: Phase 4
Study type: Interventional

The investigators propose that patients who receive targeted pharmacotherapy (sertraline) or focused psychotherapy (cognitive behavioral therapy-informed psychotherapy (CBT-ip) for NES) or combined treatment (CBT-ip + sertraline) will report fewer nonepileptic seizures (NES) compared to patients who receive community care / treatment as usual (TAU). The purpose of this study is to provide pilot testing and data to inform the future multicenter randomized controlled trial based on the hypothesis.

NCT ID: NCT00830531 Completed - Seizures Clinical Trials

Pilot Study of Bumetanide for Newborn Seizures

Start date: January 2010
Phase: Phase 1
Study type: Interventional

The main goal of the study is to obtain pharmacokinetic and safety data of bumetanide in newborns with refractory seizures. The overall hypothesis is that bumetanide, added to conventional antiepileptic (antiseizure) medications, will be a safe and well tolerated medication, compared with conventional antiepileptic drugs alone.

NCT ID: NCT00827320 Completed - Seizures Clinical Trials

Bioequivalency Study of Levetiracetam 1g Tablets Under Fed Conditions

Start date: June 2007
Phase: N/A
Study type: Interventional

The objective of this study was to prove the bioequivalence of Levetiracetam 1000 mg Tablets under fed conditions

NCT ID: NCT00826865 Completed - Seizures Clinical Trials

Bioequivalency Study of Levetiracetam 750 mg Tablets Under Fasting Conditions

Start date: August 2005
Phase: N/A
Study type: Interventional

The objective of this study was to prove the bioequivalence of Levetiracetam 750 mg Tablets under fasted conditions

NCT ID: NCT00826787 Completed - Seizures Clinical Trials

Bioequivalency Study of Levetiracetam 750 mg Tablets Under Fed Conditions

Start date: August 2005
Phase: N/A
Study type: Interventional

The objective of this study was to prove the bioequivalence of Levetiracetam 750 mg Tablets under fed conditions

NCT ID: NCT00826722 Completed - Seizures Clinical Trials

Bioequivalency Study of Levetiracetam 1g Under Fasted Conditions

Start date: June 2007
Phase: N/A
Study type: Interventional

The objective of this study was to prove the bioequivalence of Levetiracetam 1000 mg Tablets under fasted conditions

NCT ID: NCT00789113 Completed - Epilepsy Clinical Trials

Determination of Absorption and Elimination of Lamotrigine-XR

Start date: November 2008
Phase: Phase 1/Phase 2
Study type: Interventional

People over 65 years of ag break down (metabolize) drugs differently than younger adults. It is not known why this happens or how elderly people absorb or break down these drug differently. These difference may show that elderly individuals need lower doses of medications to avoid possible toxicity. We are interested in studying how yor body absorbs and breaks down your lamotrigine medication. This research may indicate that doses of lamotrigine should be lowered as people get older.

NCT ID: NCT00771927 Completed - Epilepsies, Partial Clinical Trials

Post-Authorization Safety Study to Assess the Safety of Vimpat as add-on Therapy in Patients With Partial-onset Seizures

PASS
Start date: October 2008
Phase: N/A
Study type: Observational

SP942 is a non-interventional post-authorization safety study (PASS) to evaluate the long-term safety and tolerability of Vimpat® (Lacosamide, LCM) as add-on treatment in patients with Epilepsy 16 years and older with partial-onset seizures who are uncontrolled on current therapy. Using reported adverse events, the incidence of certain cardiovascular and psychiatric events will be evaluated.