Reduce Sedentariness and Enhance Psychological Well-being of Office Workers With TCM-based Intervention

Sedentary Behavior Clinical Trial

Official title:

Reduce Sedentariness and Enhance Physical and Psychological Health of Office Workers With TCM-based Anti-sedentary Intervention: Efficacy and Potential Psychophysiological Mechanisms

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06183125
• Other study ID #: V2023
• Status: Not yet recruiting
• Phase: N/A
• Start date: March 20, 2024
• Est. completion date: December 31, 2024

Study information

• Verified date: March 2024
• Source: The Hong Kong Polytechnic University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The goal of this clinical trial is to test the effects of a TCM-based anti-sedentariness program on workplace sitting time, perceived stress, and cortisol in office workers.The main questions it aims to answer are:

1. Can a Traditional Chinese Medicine (TCM)-based anti-sedentariness program effectively reduce workplace sitting time, perceived stress and cortisol levels among office workers?

2. Whether such anti-sedentary effect works through stress management and enhances when holistic thinking is endorsed.

Participants will engage in a 4 week TCM-based program intervention including 2 weeks of health education and promotion activities (understanding sedentary behaviors, Baduanjin, acupressure, dantian breathing, and mindfulness) and 2 weeks of supported self-practice (daily reminders and tips, regular feedback on sitting time, and individual consultation).

Researchers will compare a group receiving a Traditional Chinese Medicine (TCM)-based intervention with a wait-list control group to determine the effectiveness of the intervention in reducing sitting time and enhancing physical and psychological health.

Description:

Introduction:

Sedentary behaviors and their associated physical and mental health risks among adults have received growing concerns among the clinical and research communities. Office workers commonly engage in sedentary behaviors due to their long stationary hours. Evidence has revealed that higher levels of sedentary behaviors were associated with higher perceived stress levels at workplace. However, scarce studies focused on the role of stress management in reducing sedentary behaviors. Traditional Chinese medicine (TCM)-based body works (such as dantian breathing, qigong, and acupressure) are low-cost techniques and found to be primising in addressing stress and sedentary behaviors at workplace. The health benefits of TCM-based bodywork in sedentary office workers may be enhanced when the workers endorse holistic thinking.

The present research aims to test the effects of a TCM-based anti-sedentariness program on workplace sitting time, perceived stress, and cortisol in office workers. Investigators will also explore the psychophysiological mechanism whether such anti-sedentary effect works through stress management and enhances when holistic thinking is endorsed.

Methods:

A systematic review and meta-analysis has been conducted to synthesize the pooled effect of existing anti-sedentariness interventions on office workers' sitting time and compare the effectiveness of different intervention types in reducing sedentary behaviors relative to the control group. The systematic review and meta-analysis set the theoretical foundation of intervention elements for the reduction of sedentary behaviors at workplace and their psychological effects to be applied in the present study.

A randomized controlled trial will be conducted among 92 office workers with self-reported sitting time of 5.5 hours or longer per workday. Participants will be randomly assigned to intervention (TCM-based program) and wait-list control groups. The TCM-based program will last for 4 weeks, with 2 weeks of health education and promotion activities (understanding sedentary behaviors, Baduanjin, acupressure, dantian breathing, and mindfulness) and 2 weeks of supported self-practice (daily reminders and tips, regular feedback on sitting time, website support and individual consultation). Participants' sitting time per workday and perceived stress will be assessed at baseline, post-intervention (4 weeks after baseline), and follow-up (6 weeks after baseline). During the 2-week self-practice, participants in the intervention group will complete a diary of self-practice duration of TCM-based bodywork, perceived stress, and collect saliva samples every two days. Repeated-measures ANOVA will be used to test the group differences in changes in sitting time and perceived stress. Mediating effects of perceived stress and cortisol and moderating effects of holistic thinking will be explored through SPSS marcos.

Significance:

The findings of this study will provide valuable insights into the effectiveness of a TCM-based intervention in reducing sedentary behavior and improving psychological well-being. It is innovative to understand the psychophysiological mechanism of reducing sedentary behavior to explore tailored interventions to enhance the health quality of office workers. Given the easy practice and low cost of the TCM-based body works, the project can put forward a cost-effective intervention that can benefit a large population sustainably.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 92
• Est. completion date: December 31, 2024
• Est. primary completion date: December 30, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

1. Aged 18 or above with a full-time and office-based job

2. Reported >5.5 hours of sitting per day at work

3. Native Chinese speaker (Cantonese or Mandarin)

4. Be able to give consent

Exclusion Criteria:

1. Have severe or chronic illness and not suitable for physical exercise

2. Be oversensitive to tactile stimulation

3. Have regular practice of qigong, acupressure, or mindfulness-based activities during the 4 weeks prior to recruitment

Related Conditions & MeSH terms

• Sedentary Behavior

Intervention

Behavioral:
• Traditional Chinese Medicine-based program
Week1-2: one health talk session(60 mins); three workshops (each workshop will last for 60-90mins) to provide hands-on training in Baduanjin, acupressure techniques, mindful stretching, and effective strategies to combat sedentary behavior in the workplace. Week 3-4: group practice sessions will take place for one hour every other day throughout the workweek; website support.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
The Hong Kong Polytechnic University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	sedentary behavior- total sitting time/workday	measured by Actigraph wGT3X-BT	Baseline, week 5, week 9
Primary	sedentary behavior- sitting time/9-h working time	measured by Actigraph wGT3X-BT	Baseline, week 5, week 9
Primary	Self-report sedentary behaviors	measured by International Physical Activity Questionnaire (IPAQ short version) with 8 items. Physical activity levels can be classified as low intensity when the weekly MET (metabolic equivalent of task) value is less than 600, moderate intensity when it ranges from 600 to 3000 MET, and high intensity when it exceeds 3000 MET per week.	Baseline, week 5, week 9
Primary	psychological stress	measured by perceived stress scale(PSS) with 10 items. Each item in the PSS questionnaire is rated on a five-point Likert scale, ranging from 0 (never) to 4 (very often). Participants are asked to indicate the frequency with which they have experienced each event over the past month.The total score on the PSS can range from 0 to 40. Higher scores indicate a higher level of perceived stress.	Baseline, week 5, week 9
Primary	physiological stress	measured by salivary cortisol concentration(measured in ng/mL)	Baseline, week 5, week 9
Secondary	Holistic thinking	measured by Analysis-Holism Scale (AHS), which consists of 24 items. Items are rated on a scale ranging from 1 to 7 (1 = strongly disagree, 7 = strongly agree). The total score on the AHS can range from 24 to 168. Higher scores indicate greater holistic cognitive style, and lower scores indicate greater analytic cognitive style.	Baseline
Secondary	Health-related quality of life	measured by The Chinese (Hong Kong) SF-36 Health Survey. It consists of 36 questions that cover eight different domains: physical functioning, role limitations due to physical health problems, bodily pain, general health perceptions, vitality, social functioning, role limitations due to emotional problems, and mental health. A higher score indicates better quality of life.	Baseline, week 5, week 9
Secondary	Sleep quality	measured by The Pittsburgh Sleep Quality Index, PSQI.The Pittsburgh Sleep Quality Index consists of 19 individual items, with a total score of 21 and a higher score indicating poorer sleep quality.	Baseline, week 5, week 9
Secondary	Psychological distress	measured by Depression Anxiety Stress Scale(DASS).The DASS-21 consists of 21 items, with seven items dedicated to each of the three subscales: depression, anxiety, and stress. A higher score indicates more depression, anxiety and stress.	Baseline, week 5, week 9
Secondary	Self efficay	measured by The Chinese Self-Efficacy Scale. It consists of 10 items.The total score is calculated by finding the sum of the all items. For the GSE, the total score ranges between 10 and 40, with a higher score indicating more self-efficacy.	Baseline, week 5, week 9
Secondary	Blood pressures	Systolic and diastolic blood pressure will be measured by Omron blood pressure monitor.	Baseline, week 5, week 9
Secondary	Hand grip strength	measured by Jamar handheld dynamometer	Baseline, week 5, week 9
Secondary	IL-6	Collect saliva samples to assay IL-6 concentration by using enzyme-linked immunoassay according to the manufacturer's instruction.	Baseline, week 5, week 9
Secondary	IL-1ß	Collect saliva samples to assay IL-1ß concentration by using enzyme-linked immunoassay according to the manufacturer's instruction.	Baseline, week 5, week 9