Controlled Trial: 5-day Course of Rifampin Versus Doxycycline for the Treatment of Mild to Moderate Scrub Typhus

Scrub Typhus Clinical Trial

Official title: Controlled Trial: 5-day Course of Rifampin Versus Doxycycline for the Treatment of Mild to Moderate Scrub Typhus

Status Completed

Clinical Trial Summary

New antibiotics are required to have not only the antibacterial activity against doxycyline-resistant O. tsutsugamushi but also lower risk for resistance or any cross-resistance to others.

In this prospective, open-label, randomized trial, we enroll patients with mild-to-moderate scrub typhus. We compared the efficacy and safety of a 5-day rifampin therapy with those of a 5-day doxycycline therapy at Chosun University Hospital, or one of its two community-based affiliated hospitals which are all located in southwestern Korea between 2006 and 2009.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Scrub Typhus

• NCT number: NCT00568711
• Study type: Interventional
• Source: Chosun University Hospital
• Status: Completed
• Phase: N/A
• Start date: September 2006
• Completion date: December 2009