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Scorpion Stings clinical trials

View clinical trials related to Scorpion Stings.

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NCT ID: NCT06333834 Not yet recruiting - Clinical trials for Centruroides Envenomation

Assessment of the Efficacy of Scorpion Antivenom Therapy in a Dose-response Manner, in Patients With Scorpionism

Start date: June 15, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

The clinical study aims to compare the effectiveness of applying two different regimens of scorpion antivenom therapy. In the first regimen (control), the medication is administered to all patients, and depending on the severity of the condition, the dosage varies. In the experimental regimen, an identical dose of scorpion antivenom is administered to patients exhibiting signs and symptoms of scorpion sting intoxication, in addition to pain and other symptoms at the sting site. The primary response variable is the time taken for signs and symptoms to resolve, but differences in complications, adverse effects, venom and antivenom concentration in the blood, and the need for other therapeutic measures are also evaluated.

NCT ID: NCT05125796 Completed - Scorpion Stings Clinical Trials

Analgesic Use for Pain Relief in Scorpion Sting

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

In scorpion stings, patients mostly apply with the complaint of pain. Emergency physicians need to relieve this pain quickly.

NCT ID: NCT04571411 Not yet recruiting - Scorpion Stings Clinical Trials

Severity of Scorpion Sting in Relation to Hematological Parameters

Start date: December 1, 2020
Phase:
Study type: Observational

The aim of this study is to investigate the relationship between severity of envenomation and hematological parameter by detectig initial mean platelet volume (MPV), neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) in pediatric patients presenting with a scorpion sting.

NCT ID: NCT03943199 Completed - Pain Clinical Trials

Comparison of Lysine Clonixinate, Ketorolac and Metamizole Sodium in Scorpion Stings

Start date: May 5, 2019
Phase: N/A
Study type: Interventional

The cases of scorpion stings are matters of medical importance, where Mexico is considered as one of the main countries of such public health problem.

NCT ID: NCT03622125 Completed - Scorpion Stings Clinical Trials

Decrease in Temperature as a Pagtonomic Sign by Scorpion Sting

Start date: May 20, 2017
Phase:
Study type: Observational

The scorpion sting is a medical disease, for the signs and symptoms presented; Sometimes patients do not know the animal that causes these symptoms; the bibliography marks the decrease in temperature as a sign to be presented.

NCT ID: NCT01599936 Completed - Clinical trials for Scorpion Sting Envenomation

Open Label Clinical Trial of Alacramyn® in Pediatric Patients With Scorpion Sting Envenomation

Start date: April 2004
Phase: Phase 3
Study type: Interventional

There is no FDA approved therapy for the treatment of scorpion envenomation. Centruroides scorpion envenomation produces a pattern of neurotoxicity with a spectrum of severity ranging from trivial to life threatening. Patients stung by Centruroides scorpions develop a clinical syndrome which may require sedation with benzodiazepines and observation for 6 to 28 hours of intensive care monitoring. A safe therapy is necessary to halt the progression of symptoms early in the clinical course while avoiding the clinical deterioration that can occur en route to a tertiary facility. Alacramyn® is anticipated to be safer and more effective than the present standard of care, midazolam, and faster-acting thus eliminating the need to transport most rural patients and reducing hospitalization time.

NCT ID: NCT01599923 Completed - Clinical trials for Scorpion Sting Envenomation

Open Label Study of Alacramyn® in Pediatric Patients With Scorpion Sting Envenomation

Start date: May 2005
Phase: Phase 3
Study type: Interventional

There is no FDA approved therapy for the treatment of scorpion envenomation in the United States. Centruroides scorpion envenomation produces a pattern of neurotoxicity with a spectrum of severity ranging from trivial to life threatening. Patients stung by Centruroides scorpions develop a clinical syndrome which may require sedation with benzodiazepines and observation for 6 to 28 hours of intensive care monitoring. A safe therapy is necessary to halt the progression of symptoms early in the clinical course while avoiding the clinical deterioration that can occur en route to a tertiary facility. Alacramyn® is anticipated to be safer and more effective than the present standard of care in the United States, midazolam, and faster-acting thus eliminating the need to transport most rural patients and reducing hospitalization time.

NCT ID: NCT01415830 Completed - Scorpion Sting Clinical Trials

Compare Two Anti-Scorpion Venom Serum In Children

Start date: August 2011
Phase: Phase 3
Study type: Interventional

The morbidity associated with scorpion sting intoxication presents an endemic pattern in the country, where there are highly venomous species of scorpions so the scorpion sting intoxication (IPPA) is considered a medical emergency. On the other hand, there is scarce scientific literature from different controlled studies evaluating anti-scorpion serum, considering clinical severity scales, lab results and their safety. The aim of this study is to compare the efficacy and safety of scorpion sting treatment, using two sera, one produced by Birmex versus Alacramyn ® (Bioclon).

NCT ID: NCT01336660 Completed - Clinical trials for Poisoning by Scorpion Sting

A Trial of Equine F (ab')2 Antivenom for Treatment of Scorpion Envenomation in Morocco

Start date: July 21, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

This study has the objective to demonstrate the effectiveness of Alacramyn NAMO in the treatment of North Africa and Middle East scorpions envenomation by reducing the severity of envenomation. The primary endpoint is make a comparison between antivenom and placebo groups, at 4 hours after study drug, of the number of cases showing improvement in class of envenomation.

NCT ID: NCT00739440 Completed - Scorpion Sting Clinical Trials

Randomized Controlled Trial to Compare Two Anti-scorpion Serums

Start date: August 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the efficiency and safety of the treatment against sting scorpion, using two serums, one elaborated by Birmex versus other commercial serum