Clinical Trials Logo
  1. Home
  2. Schizophrenia; Psychosis
  3. NCT06341517

Brain Circuitry Therapeutics for Schizophrenia — ATHENA  

Schizophrenia; Psychosis Clinical Trial

Official title:
Brain Circuitry Therapeutics for Schizophrenia - A Cross-species Longitudinal Randomized Controlled Clinical Study to Treat Negative Symptoms of Schizophrenia Using Non-invasive Stimulation of the Cerebellum

Clinical Trial Summary

This project is a double blind randomized clinical trials that examines the efficacy of cerebellar non invasive stimulation for apathy improvement in patients with schizophrenia

Clinical Trial Description

This double-blind RCT aims to explore the efficacy of intensiveTranscranial Magnetic Stimulation (TMS) in schizophrenia spectrum disorders. Previous studies in various disorders suggest that intensive TMS is efficacious and safe. Participants will undergo neuronavigated intermittent theta burst TMS, targeted to individual network targets, at an accelerated protocol (multiple sessions a day), The primary goal is to determine the efficacy of this protocol in alleviating negative symptoms of schizophrenia. Additionally, the study will measure the impact of accelerated TMS on a range of clinical and cognitive outcomes, along with neuroimaging markers indicative of symptom response. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06341517
Study type Interventional
Source University of Geneva, Switzerland
Contact
Status Not yet recruiting
Phase N/A
Start date November 5, 2024
Completion date December 12, 2027
View Details
See also
  Status Clinical Trial Phase
Completed NCT04559529 - Pharmacological Modulation of Hippocampal Activity in Psychosis 2 Phase 2
Recruiting NCT06134661 - Accelerated rTMS for Psychomotor Slowing N/A
Completed NCT05759091 - Effect of Applying Cognitive Defusion Techniques on Mindful Awareness, Cognitive Fusion and Believability of Delusions Among Clients With Schizophrenia N/A
Not yet recruiting NCT05995457 - The IM-ZBULLE Study : " Z-track " and " Airlock " Techniques During Intramuscular Injection of Haloperidol Decanoate N/A
Completed NCT04777266 - Music Therapy for People With Schizophrenia and Relates Psychosis. N/A
Not yet recruiting NCT05550155 - Efficacy of Maintenance Repetitive Transcranial Magnetic Stimulation (rTMS) in Auditory Verbal Hallucinations N/A
Terminated NCT04277936 - Pharmacologic Modulation of Hippocampal Activity in Psychosis Phase 2
Active, not recruiting NCT04748679 - Cognitive Behavioral Therapy (CBT) Study Evaluating the Updating of Persecutory Beliefs N/A
Recruiting NCT05858255 - Hjernegym - Effects of Exergaming in Psychosis: a Clinical Intervention Study N/A
Not yet recruiting NCT05763966 - Uppsala Psychosis Cohort
Not yet recruiting NCT05731414 - Outcomes From Remediation and Behavioural Intervention Techniques N/A
Completed NCT04898270 - Adjunctive Use of Fute (Flupentixol) in Multi-acting Receptor-targeted Antipsychotics Treated Schizophrenia Patients Phase 4
Completed NCT04659161 - A Study to Assess Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Adult Patients With Schizophrenia (EMERGENT-2) Phase 3
Completed NCT04260763 - Evaluating a Novel Mobile App for Social Cognition in Psychosis N/A
Recruiting NCT04853485 - Repetitive Transcranial Magnetic Stimulation in Early Psychosis and The Functional Connectivity Biotypes N/A
Completed NCT04738123 - A Study to Assess Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Adult Patients With Schizophrenia (EMERGENT-3) Phase 3
Recruiting NCT05445180 - Investigating the Neural Correlates of Cognitive Function in Psychosis Patients and Non-Psychiatric Controls With Cannabis Use N/A
Not yet recruiting NCT06375902 - The Fragility of Metaphors (FraMe): Learning, Loosing, and How to Train Them
Completed NCT04773171 - Efficacy of Computer-assisted Cognitive Remediation in Patients With Schizophrenia N/A