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SARS-CoV-2 clinical trials

View clinical trials related to SARS-CoV-2.

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NCT ID: NCT05876364 Active, not recruiting - COVID-19 Clinical Trials

Study to Assess Safety, Reactogenicity and Immunogenicity of the repRNA(QTP104) Vaccine Against SARS-CoV-2(COVID-19)

Start date: November 19, 2021
Phase: Phase 1
Study type: Interventional

This study is to evaluate the safety, reactogenicity, and immunogenicity of the QTP104 vaccine against SARS-CoV-2 infection in healthy adults.

NCT ID: NCT05870839 Active, not recruiting - SARS-CoV-2 Clinical Trials

Study of VXCO-100, a SARS-CoV Candidate Vaccine in Healthy Adults in the United States

Start date: May 11, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and immunogenicity of ascending dose levels of VXCO-100 in healthy adults.

NCT ID: NCT05827926 Active, not recruiting - Influenza Clinical Trials

A Study of mRNA-based Influenza and SARS-CoV-2 (COVID-19) Multi-component Vaccines in Healthy Adults

Start date: April 14, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to generate sufficient safety, reactogenicity, and immunogenicity data to enable selection of an mRNA-1083 vaccine composition and dose level to evaluate in a subsequent Phase 3 clinical trial in adults.

NCT ID: NCT05799651 Active, not recruiting - SARS-CoV-2 Clinical Trials

Safety and Immunogenicity of Glycovax-002 Vaccine in Healthy Adults

Start date: April 28, 2023
Phase: Phase 1
Study type: Interventional

Glycovax Pharma has developed a glycoconjugate vaccine candidate called Glycovax-002 to fight the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the origin of COVID-19. The aim of the study is to assess the safety, reactogenicity and immunogenicity of Glycovax-002 in humans. The study is a phase I, placebo-controlled, dose-escalation study conducted in 36 healthy females and males aged between 18 and 55 years old. The vaccine will be administered three times with a two-week time interval between each dose. Dose escalation is conducted in three steps. At each step, 9 participants receiving the vaccine will be randomized with 3 participants receiving placebo (normal saline). Progression to next step is conditional to a DSMB's approval.

NCT ID: NCT05764083 Active, not recruiting - COVID-19 Clinical Trials

Epidemiology, Immunology and Clinical Characteristics of COVID-19 (EPIC3)

EPIC3
Start date: July 22, 2020
Phase:
Study type: Observational [Patient Registry]

The purpose of this research is to gather information to answer questions about the Coronavirus Disease 2019 (COVID-19) which is caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection. This study will collect information and biological specimens from participants who have been tested for the SARS-CoV-2 infection. By doing this study, the investigators hope to learn important new information about SARS-CoV-2 infections and the potentially severe outcomes of COVID-19 to find better ways to manage and treat it in the future. The investigators also hope to learn what makes some people more susceptible to infection to help better inform Veterans on how to reduce their risk of infection. This study also involves the development and maintenance of a participant registry, a data repository, and a biorepository for future research.

NCT ID: NCT05550142 Active, not recruiting - SARS-CoV-2 Clinical Trials

A Preliminary Exploratory Cohort Study of SARS-CoV-2 Variant (Omicron BA.5) mRNA Vaccine in Participants Aged 18 Years and Over in China

Start date: September 16, 2022
Phase: N/A
Study type: Interventional

This is a preliminary exploratory cohort study to evaluate safety, tolerability and immunogenicity of SARS-CoV-2 Variant (Omicron BA.5) mRNA Vaccine (LVRNA012) in participants aged 18 years and over in China.

NCT ID: NCT05547256 Active, not recruiting - SARS-CoV-2 Clinical Trials

A Preliminary Exploratory Cohort Study of COVID-19 mRNA Vaccine, Bivalent in Participants Aged 18 Years and Over in China

Start date: September 13, 2022
Phase: N/A
Study type: Interventional

This is a preliminary exploratory cohort study to evaluate safety, tolerability and immunogenicity of COVID-19 mRNA Vaccine, Bivalent (LVRNA021) in participants Aged 18 years and over in China

NCT ID: NCT05547243 Active, not recruiting - SARS-CoV-2 Clinical Trials

A Cohort Study of COVID-19 mRNA Vaccine, Bivalent in Participants in China

Start date: September 26, 2022
Phase: N/A
Study type: Interventional

This is a cohort study to evaluate safety and immunogenicity of COVID-19 mRNA Vaccine, Bivalent (LVRNA021) in participants aged 18 years and over in China

NCT ID: NCT05397223 Active, not recruiting - SARS-CoV-2 Clinical Trials

A Study of Modified mRNA Vaccines in Healthy Adults

Start date: May 24, 2022
Phase: Phase 1
Study type: Interventional

The main goal of this study is to evaluate the safety, reactogenicity, and immunogenicity of study vaccines.

NCT ID: NCT05354089 Active, not recruiting - SARS-CoV-2 Clinical Trials

A Study of SARS-CoV-2 mRNA Vaccine (SYS6006) in Chinese Healthy Adults Aged 18 -59 Years.

Start date: April 27, 2022
Phase: Phase 1
Study type: Interventional

This is a phase I, randomized, observer-blinded, placebo-controlled and dose-escalation clinical trial to evaluate the safety, tolerability, immunogenicity and immune persistence of SYS6006 (SARS-CoV-2 mRNA Vaccine) in 18-59 year old healthy population.