Chronic Fatigue in Sarcoidosis

Status Completed

Clinical Trial Summary

Background: Chronic fatigue (CF) is a prominent symptom in many sarcoidosis patients, affecting quality of life (QoL) and interfering with treatment. This study investigates neuropsychobiological mechanisms and markers of CF in sarcoidosis.

Clinical Trial Description

Patients with a histological diagnosis of sarcoidosis are included. The Multidimensional Fatigue Inventory (MFI) is used to define patients with and without CF. All patients are then characterized using several fatigue, depression, QoL and executive functioning questionnaires. Cognitive functioning and underlying neural correlates are assessed using an n-back task measuring working memory and (sustained) attention during functional magnetic resonance imaging (fMRI). Sarcoidosis disease activity is determined using lung function, laboratory parameters, and exercise capacity. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04178239
Study type	Observational
Source	RWTH Aachen University
Contact
Status	Completed
Phase
Start date	March 10, 2017
Completion date	February 2, 2018

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