ACTHAR Gel for Cutaneous Sarcoidosis: An Open Label Trial

Status Not yet recruiting

Clinical Trial Summary

ACTHAR gel has efficacy in the treatment of cutaneous sarcoidosis

Clinical Trial Description

Sarcoidosis is a multisystem granulomatous disease of unknown cause. Although sarcoidosis most commonly affects the lung3, it may affect any organ. Although corticosteroids are recognized as the drug of choice for sarcoidosis, ACTH is the only drug that is FDA-approved for this disorder. However, there is limited data on the efficacy of ACTH for this condition.

Presently, corticosteroids as considered the drug of choice for the treatment of cutaneous sarcoidosis. However, ACTHER GEL not only has obvious anti-inflammatory effects by resulting in corticosteroid production, but it may also activate melanocortin receptors. The melanocortin system has powerful anti-inflammatory properties that may be beneficial in the treatment of cutaneous sarcoidosis. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02348905
Study type	Interventional
Source	Albany Medical College
Contact	Haroon Chaudhry, MBBS
Phone	518-262-1542
Email	chaudhh@mail.amc.edu
Status	Not yet recruiting
Phase	Phase 2/Phase 3
Start date	March 2015
Completion date	January 2016

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