Sarcoidosis Clinical Trial
Official title:
CArdiac Sarcoidosis Response TO steRoids (CASTOR) Trial
There are no published clinical consensus guidelines on the treatment of cardiac
sarcoidosis. Corticosteroid therapy is advocated by some experts, but is based on small
observational studies, with varied clinical response.
Objectives of this trial:
- to systemically assess the response of patients with cardiac sarcoidosis, to treatment
with corticosteroids
- to identify the clinical predictors of response to treatment with corticosteroids
- to assess the utility of imaging with PET and MRI to predict response to treatment with
corticosteroids
- to determine the prevalence of cardiac sarcoidosis in young patients with unexplained
heart block and in patients with unexplained dilated cardiomyopathy associated with
ventricular tachycardia
- to use the data from this pilot study to assess the need, feasibility, and sample size
for a larger multicentre trial
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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