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NCT00837668 Clinical Trial

Stromal Gene Expression During Pulmonary Sarcoidosis

Sarcoidosis Clinical Trial

Official title:
Stromal Gene Expression During Pulmonary Sarcoidosis

Clinical Trial Details — Status: Terminated

Administrative data
NCT number NCT00837668
Other study ID # 2005H0018
Secondary ID
Status Terminated
Phase N/A
First received February 4, 2009
Last updated June 12, 2017
Start date April 2005
Est. completion date February 2012

Study information
Verified date June 2017
Source Ohio State University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

to determine the genetic pathways operating at the tissue level to cause granulomatous inflammation in the lungs and lymph nodes of patients with sarcoidosis. By so doing, we hope to identify unique genetic mechanisms which will aid in the diagnosis of sarcoidosis and will help us understand the pathogenesis of this poorly understood disease.

Description:

to collect small sample of lung tissue recovered from a clinical procedure such as bronchoscopy, or a mediastinoscopy (a procedure in which a lighted instrument (mediastinoscope) is inserted through a neck incision to visually examine the structures in the top of the chest cavity and to take a sample (biopsy) of tissue.

Recruitment information / eligibility
Status Terminated
Enrollment 110
Est. completion date February 2012
Est. primary completion date February 2012
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:

- diagnosis of sarcoidosis

Exclusion Criteria:

- inability to provide consent

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United States The Ohio State University Columbus Ohio

Sponsors (1)
Lead Sponsor Collaborator
Ohio State University

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary To Identify Gene Expression Patterns That Specifically Correlate With Active Pulmonary Sarcoidosis. end of study
Secondary To Determine if Gene Expression Patterns Correlate With The Severity of Illness Of Sarcoidosis Patients end of study
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