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Safety Issues clinical trials

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NCT ID: NCT03582553 Completed - Pharmacokinetics Clinical Trials

Safety and Pharmacokinetics of an Extract of Naringenin

Citrus
Start date: May 25, 2018
Phase: Early Phase 1
Study type: Interventional

This study evaluates the safety of administering single ascending doses (150, 300, 600, and 900 mg) of a citrus extract of the flavonoid narigenin, and assesses the blood concentrations of naringenin following oral administration of the extract.

NCT ID: NCT03577743 Completed - Safety Issues Clinical Trials

Effect of Bevacizumab in Metastatic Triple Negative Breast Cancer

Start date: July 1, 2018
Phase: Phase 2
Study type: Interventional

Evaluating efficacy and safety of bevacizumab when combined with chemotherapy (carboplatin and Paclitaxel ) in treatment of patient with metastatic triple negative breast cancer

NCT ID: NCT03565861 Completed - Safety Issues Clinical Trials

Safety and Pharmacokinetics of NP10679 in Normal Healthy Volunteers

Start date: April 6, 2018
Phase: Phase 1
Study type: Interventional

This study assesses the safety, tolerability and pharmacokinetics of NP10679 when delivered intravenously in escalating dose levels in comparison to placebo.

NCT ID: NCT03556670 Active, not recruiting - Health Behavior Clinical Trials

Active Workplace Study

Start date: July 10, 2018
Phase: N/A
Study type: Interventional

Exposure to sedentary work is an occupational hazard with significant health and safety consequences. Sedentary behavior is an independent predictor of heart disease, diabetes, early mortality, and accounts for the majority of the increase in obesity in the US. Prolonged sitting, common in modern sedentary work environments, contributes to increases in musculoskeletal pain, injuries, and detrimental changes in physiological functioning. Call center employees, who are among the most sedentary workers in the US, area priority population for Total Worker Health interventions. This project is designed to substantially improve health, safety, and well-being in call center employees, including physiological outcomes that contribute to chronic diseases.The study tests whether a Total Worker Health oriented intervention is more effective than usual practices for increasing the utilization of health and safety resources and improving worker health and safety. Study results will have implications for over 30 million sedentary workers in the US.

NCT ID: NCT03527615 Recruiting - Safety Issues Clinical Trials

Clinical Pharmacist Anticoagulant Stewardship

Start date: January 1, 2017
Phase:
Study type: Observational

Initiative to improve direct anticoagulant utilization involving programmatic review by clinical pharmacists in collaboration with multidisciplinary team.

NCT ID: NCT03488186 Completed - Safety Issues Clinical Trials

PK-PD Comparative Study of Lansoprazole Capsules and Lansoprazole Enteric-coated Capsules in Healthy Chinese Volunteers

Start date: July 19, 2018
Phase: Phase 1
Study type: Interventional

The objective of this study was to compare the relative PK-PD of Lansoprazole Capsules and Lansoprazole DR Capsules in healthy Chinese volunteers.

NCT ID: NCT03488173 Completed - Safety Issues Clinical Trials

Pharmacokinetic Study of Lansoprazole Capsules in Healthy Chinese Volunteer

Start date: April 23, 2018
Phase: Phase 1
Study type: Interventional

The objective of this study was to compare pharmacokinetic of Lansoprazole Capsules 30 mg with Lansoprazole Capsules of Takeda 30 mg in healthy adult human subjects.

NCT ID: NCT03473236 Completed - Safety Issues Clinical Trials

Phase 1A Safety Trial of Inhaled PK10571 (GB002)

Start date: September 6, 2017
Phase: Phase 1
Study type: Interventional

This is a phase 1A randomized double blind placebo controlled single ascending dose and multiple ascending dose trial of inhaled PK10571 (GB002) in healthy adult subjects.

NCT ID: NCT03465475 Completed - Safety Issues Clinical Trials

Anesthetic Cost Analysis With Desflurane in Automated Gas Control Mode

Start date: July 1, 2018
Phase:
Study type: Observational

Inhalation agents constitute the major part of anesthetic drug costs (20% - 25%) and a significant portion of the applied inhalation agents are thrown into the atmosphere through the waste gas system without being absorbed by the patient. The amount of waste gas is directly correlated to the fresh gas flow (FGF). Reducing the TGA during general anesthesia reduces the consumption of inhalant agents and contributes to the reduction of greenhouse gas pollution. Risks such as hypoxia, hypercapnia, inadequate depth of anesthesia and potential toxic gas accumulation were associated with low flow anesthesia, but the patient was provided with adequate safety by following pulse oximetry, capnography, FiO2 and anesthetic gas analysis. We aimed to perform anesthetic cost analysis and patient security in automated gas control mode (AGC).

NCT ID: NCT03462108 Completed - Safety Issues Clinical Trials

Safety and Immunogenicity of Rotavirus (Bio Farma) Vaccine in Adults, Children & Neonates

Start date: April 9, 2018
Phase: Phase 1
Study type: Interventional

This study is to assess the safety of Rotavirus (Bio Farma) vaccine in adults, children and neonates.