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Safety Issues clinical trials

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NCT ID: NCT03908957 Completed - Safety Issues Clinical Trials

to Assess the Safety of Ga68-Dolacga Injection in Healthy Volunteers

Start date: February 12, 2019
Phase: Phase 1
Study type: Interventional

This is a phase 1 study to evaluate the safety of Ga68-Dolacga Injection in healthy volunteers and to assess the normal reference range and inter-individual variability of the Ga68-Dolacga Injection in estimating liver reserve in healthy volunteers.

NCT ID: NCT03838341 Recruiting - Atrial Fibrillation Clinical Trials

Stand-alone Totally Thoracoscopic Left Atrial Appendage Occlusion Using AtriClip® Device in Non-valvular Atrial Fibrillation.

THORACS-LAAO
Start date: June 8, 2015
Phase:
Study type: Observational [Patient Registry]

Polish multicenter registry to assess safety and durability of totally thoracoscopic left atrial appendage occlusion for stroke prevention in atrial fibrillation.

NCT ID: NCT03799393 Completed - Safety Issues Clinical Trials

Buckle Me Up!: A Digital Emergency Department Discharge Intervention for Child Car Safety

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

This study explores the utility of a tablet computer-based, individually-tailored application called Computer Intervention Authoring Software (CIAS) in the Emergency Department for discharge education on proper child car restraint safety. The investigators hypothesize that tablet-based, individually-tailored discharge instructions are more effective than current standard, one-size-fits-all, printed discharge instructions. This is a randomized, controlled, non-blinded trial of of children age 0-21 years old in the Emergency Department. Patients will be randomized to receive either (a) a brief tablet-based questionnaire followed by standard, paper discharge instructions or (b) a brief tablet-based questionnaire followed by the intervention - CIAS, a tablet-based computer program. One week after discharge, participants in both groups will receive an automatic text message and/or email message with a link to a web-based survey that will assess: knowledge of appropriate car restraints and whether the parent/patient engaged in any behavioral changes regarding child car restraint. These variables will be compared between the control and intervention groups.

NCT ID: NCT03794843 Recruiting - Safety Issues Clinical Trials

Bioavailability Comparison Study of Two Types of Nimodipine Injections in Healthy Volunteers

Start date: August 23, 2018
Phase: Early Phase 1
Study type: Interventional

A Randomized, Open-label, Single Dose, Two Formulation, Two Period, Double Cross Over Bioavailability Comparison Study of two types of Nimodipine Injections in Healthy Volunteers.

NCT ID: NCT03791372 Recruiting - Safety Issues Clinical Trials

Clinical Effect and Safety of Autologous Umbilical Cord Blood Transfusion in the Treatment of Cerebral Palsy

Start date: October 10, 2017
Phase: Phase 1
Study type: Interventional

To study the clinical efficacy and safety of autologous umbilical cord blood transfusion in the treatment of cerebral palsy.

NCT ID: NCT03789539 Active, not recruiting - Safety Issues Clinical Trials

Reactogenicity, Safety and Immunogenicity of an Universal Influenza Vaccine Uniflu

Start date: June 2, 2018
Phase: Phase 1
Study type: Interventional

This is a single-site, randomized, double-blind, placebo-controlled study of Uniflu in fifty four (54) volunteers 18-60 years of age with a dose escalation. All subjects will receive an intramuscular (IM) injection twice,with a 21 days interval between treatments.

NCT ID: NCT03760900 Completed - Safety Issues Clinical Trials

Safety of Autologous Cord Blood Cells for Preterm Infants.

Start date: January 1, 2009
Phase: Early Phase 1
Study type: Interventional

To assess the safety of autologous volume- and red blood cell (RBC)-reduced non-cryopreserved umbilical cord blood (UCB) cell infusion to preterm infants.

NCT ID: NCT03696745 Not yet recruiting - Safety Issues Clinical Trials

The Treatment of Premature Infants With Brain Injury by Autologous Umbilical Cord Blood Stem Cells

Start date: November 1, 2018
Phase: Phase 1
Study type: Interventional

To study the safety and effect of autologous umbilical cord blood stem cells for treatment brain injury

NCT ID: NCT03683953 Not yet recruiting - Safety Issues Clinical Trials

The Treatment of Bronchopulmonary Dysplasia by Intratracheal Instillation of Mesenchymal Stem Cells

Start date: September 29, 2018
Phase: Phase 1
Study type: Interventional

To study the effect and saftey of intratracheal instillation of mesenchymal stem cells for treatment BPD

NCT ID: NCT03680417 Completed - Safety Issues Clinical Trials

Reactogenicity and Protectivity Following Measles- Rubella (MR) Routine Immunization in Indonesian Infants and Children

Start date: November 16, 2017
Phase: Phase 4
Study type: Interventional

to assess safety and immunogenicity of measles-rubella (MR) routine immunization in Indonesian Children and Infants