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Sacroiliitis clinical trials

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NCT ID: NCT03689881 Recruiting - Sacroiliitis Clinical Trials

Value of Tomosynthesis for the Detection of Sacro-iliitis (TOMOS SI)

TOMOS SI
Start date: October 4, 2018
Phase: N/A
Study type: Interventional

Spondyloarthropathies (SpAs) are chronic inflammatory diseases encompassing ankylosing spondylitis, psoriatic arthritis, reactive arthritis, enteropathic arthropathy, and undifferentiated SpA. In 2001, the estimated prevalence of SpA was 1.5% worldwide. Sacroiliitis is a condition caused by inflammation within the sacroiliac joint. It is the most frequent damage of SpA depicted at imaging evaluation. Conventional radiography (X-ray) is usually used to depict the structural changes associated with sacroiliitis. However further evaluation often requires additionnal computed tomography (CT). Tomosynthesis is an Xray-based imaging technology which allows reconstruction of multiple section images from a set of projection images acquired as the x-ray tube moves along a prescribed path. The advantagee of tomosynthesis is the significant reduction of radiation dose exposure compared to CT Tomosynthesis is currently used in the field of breast imaging and pneumology. Very few studies have examined the value of tomosynthesis for osteoarticular imaging. The study aims at evaluating the diagnostic performances of tomosynthesis as compared to standard X-ray and CT, in patients with a clinical suspicion of sacroiliitis. the investigators hypothesize that tomosynthesis is superior to conventional radiography for detection of sacroiliitis and is at least equal to CT with lower irradiation.

NCT ID: NCT03631030 Active, not recruiting - Clinical trials for Osteo Arthritis Knee

Cooled RF Lesion MRI Characteristics

Start date: February 25, 2018
Phase: N/A
Study type: Interventional

This Prospective, Single-center, Pilot Study will assist in gaining an understanding of the actual CRFA lesions in an in vivo situation in areas where CRFA is utilized as a standard of care treatment option for the relief of chronic pain (cervical facet joints, thoracic facet joints, lumbar facet joints, Sacroiliac (SI) region, hip and knee).

NCT ID: NCT03564106 Completed - Pain Management Clinical Trials

Intra-articular Pulsed Radiofrequency With Steroids Injection Versus Intra-articular Steroids Injection in Chronic Sacroiliac Joint Arthritis

Start date: March 1, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

The sacroiliac joint is Located between the pelvis and base of the spine, the sacroiliac joints are strong, stable joints that allow for little movement. While these joints do not bend like a knuckle or knee, they are susceptible to degenerative arthritis. Sacroiliac joint pain is one of the most common causes of chronic low back pain, accounting for 10% to 27% of patients with chronic lower back pain. It is known to be caused by abnormal motion in this joint, namely, too much motion or too little motion. Patients with pain experience various degrees of pain in the low back, groin, buttock, or posterior thigh.

NCT ID: NCT03122119 Completed - Clinical trials for Chronic Low Back Pain

Effectiveness of Ultrasound Guided Platelet Rich Plasma Injections in the Sacroiliac Joint

Start date: May 1, 2017
Phase: Phase 4
Study type: Interventional

This prospective study will be quantitatively analyzing the effectiveness of platelet-rich-plasma (PRP) injections into the sacroiliac (SI) joint in relieving sacroiliitis and low back pain originating from the SI joint. The effectiveness of PRP injections on joint pain has been well studied in the knee and shoulder. PRP injections are performed on the SI joint commonly, but there is little research documenting their effectiveness when compared to other interventions. This study will be a small pilot study to aid in closing this knowledge gap. Additionally, these injections will be performed under ultrasound guidance. Ultrasound has been proven to be of equal reliability to fluoroscopy and has the advantage of shorter time to administer and no radiation. There will be one arm to this study. The data collected will be compared to existing studies on corticosteroid SI joint injection. The experimental arm consists of the PRP injection. The PRP will be injected into the joint using the exact same technique via physical exam, special tests, and ultrasound guidance as performed in our previous studies. The outcomes will be measured with the Numeric Rating Scale for Pain (NRS) and the Oswestry Disability Index (ODI) prior to the injection, immediately post-injection, 2 weeks, 4 weeks, 3 months, and 6 months post-injection. The investigators hypothesis is, "Platelet-Rich Plasma Injections in the Sacroiliac Joint using ultrasonography in conjunction with physical examination and Point of Maximal Tenderness will produce statistically significant pain relief for more than 3 months as measured by the Numeric Rating Scale for Pain (NRS) and Oswestry Disability Index (ODI)."

NCT ID: NCT02888938 Recruiting - Clinical trials for Structural Sacro-iliitis

Diagnosis of Structural Sacroiliitis in Patients With Suspicion of Spondyloarthritis (EchoSPA)

Passerelle
Start date: January 2015
Phase: N/A
Study type: Observational

The aims of this study are: 1° to assess the value of pelvic radiography and sacro-iliac joint (SIJ) MRI compared to CT scan of SIJ for the diagnosis of structural sacro-iliitis and 2° to quantify structural elementary lesions on MRI and for the first time on CT-scan according to a SPARCC approach in a cohort of patients with a suspicion of spondyloarthritis (ECHOSpA).

NCT ID: NCT02425631 Completed - Sacroiliitis Clinical Trials

CT Follow-Up of the SImmetry Sacroiliac Joint Fusion System

Start date: October 2014
Phase: N/A
Study type: Observational

This study will evaluate long-term follow-up of subjects implanted with the SImmetry Sacroiliac (SI) Joint Fusion System (SImmetry).

NCT ID: NCT02420041 Completed - Sacroiliitis Clinical Trials

Comparing the Effects of Ultrasound Versus Fluoroscopy for Sacroiliac Joint Injections

Start date: October 2012
Phase: N/A
Study type: Interventional

The purpose of this research project is to compare two different techniques for performing an injection of the sacroiliac joint. Although both techniques are safe and accurate, the goal of the study is to determine if one technique is better than the other with respect to improvement in a patient's pain, function, and his or her satisfaction. Additionally, the investigators want to determine if one technique is quicker and more efficient than the other.

NCT ID: NCT02098694 Completed - Clinical trials for Arthritis, Psoriatic

Physiotherapy-led Outpatient Clinic for Patients With Spondyloarthritis

Start date: June 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether patients with spondyloarthritis are more satisfied with a physiotherapy-led outpatient clinic than usual care and whether there is a difference between patients in a physiotherapy-led outpatient clinic and those in usual care regarding disease activity, function and mobility.

NCT ID: NCT01719081 Completed - Clinical trials for Sacroiliac Joint Arthritis Causing Low Back Pain

Sacroiliac Joint Injection: Comparison of Xray Versus Ultrasound

Start date: January 2012
Phase: N/A
Study type: Interventional

This project involves the assessment of the efficacy of two different image guided techniques in patients with low back pain due to arthritis of the sacroiliac joint (SIJ). Intra-articular injection of local anesthetics and steroids is performed to relieve pain originating from the SIJ. Fluoroscopy has been used traditionally for image guidance for this procedure but there is a growing interest in use of ultrasound (US) for this procedure. US avoids radiation exposure to the patient and the health care team (HCT) and is less expensive. We aim to compare procedural efficacy related outcomes for SIJ injections performed using these image-guided modalities.

NCT ID: NCT01681004 Completed - Clinical trials for Sacroiliac Joint Disruption

Investigation of Sacroiliac Fusion Treatment (INSITE)

INSITE
Start date: September 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to compare outcomes when patients with degenerative sacroiliitis (arthritis of the SI joint) and or sacroiliac disruption (abnormal separation or tearing of the sacroiliac joint)undergo either SI joint fusion with the iFuse Implant System or undergo specific, targeted non-surgical treatment of the SI joint.