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NCT05401422 Clinical Trial

Brimonidine in Rosacea

Rosacea Clinical Trial

Official title:
Efficacy and Safety of Combining Doxycycline With Pulsed Dye Laser Versus Topical Brimonidine 0.33% in the Treatment of Erythematotelangiectatic Rosacea: a Comparative Clinical and Dermoscopic Study

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05401422
Other study ID # Rosacea
Secondary ID
Status Not yet recruiting
Phase N/A
First received
Last updated
Start date May 25, 2022
Est. completion date September 15, 2022

Study information
Verified date June 2022
Source Cairo University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Rosacea is a chronic and relapsing inflammatory cutaneous disorder with highly variable prevalence worldwide.

Description:

In our study, we will compare the safety, efficacy, and adverse effects of low-dose oral doxycycline alone versus combined with pulsed dye laser or topical brimonidine in treating erythematotelangiectatic rosacea in an attempt to build a treatment strategy in a disease with complex pathogenesis.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 45
Est. completion date September 15, 2022
Est. primary completion date September 15, 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years to 60 Years
Eligibility Inclusion Criteria: - Patient with current erythematotelangiectatic rosacea Exclusion Criteria: - Pregnant females. 2-Patients on systemic steroids. 3-Patients complaining of other dermatological disorders mainly photosensitive cutaneous disorder. 4- Patients receiving any systemic treatment including retinoids for the previous 1 month or any topical treatment for the previous 2 weeks or any laser sessions for the previous 3months for erythematotelangiectatic rosacea at least.

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• treatment
types

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Cairo University

Outcome
Type Measure Description Time frame Safety issue
Primary Clinical erythema assessment scale clinical scale 3 months
Secondary Thickness of capillaries by dermoscope Assessment 3 months
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