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Rhinorrhea clinical trials

View clinical trials related to Rhinorrhea.

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NCT ID: NCT06106880 Completed - Headache Clinical Trials

Alleviation of Common Cold Symptoms

Start date: May 25, 2022
Phase: Phase 1
Study type: Interventional

Upper respiratory infections (URIs) have long posed a significant burden to the US healthcare system. Well before the coronavirus disease of 2019 (COVID-19) pandemic they have been among the most common acute outpatient illnesses, causing 75-100 million physician visits each year on average, and costing the health care system billions of dollars annually. This double-blind randomized placebo-controlled study tested the efficacy of two anti-inflammatory throat sprays against placebo and against a throat spray taken in conjunction with 325mg of aspirin, a well-known systemically administered cyclooxygenase (COX) inhibitor. Participants having common cold symptoms lasting less than two days were enrolled and given treatment to administer at home. Various common cold symptoms were assessed and measured via clinically validated self-assessment scales. Participants were screened for influenza and COVID-19 before enrollment and were excluded if found positive.

NCT ID: NCT05801393 Not yet recruiting - Clinical trials for Imaging of Active CSF Rhinorrhea

HRCT, CT Cisternography and MR Cisternography in Assessment of CSF Rhinorrhea

Start date: May 1, 2023
Phase:
Study type: Observational

To assess the diagnostic accuracy of combined high resolution CT, CT cisternography and MR cisternography in pre operative assessment of active CSF leak, compared by endoscopic sinus surgery.

NCT ID: NCT01448057 Completed - Clinical trials for Upper Respiratory Tract Infection

Evaluation of Efficacy and Safety of Tablets of Paracetamol, Dimethindene Maleate and Phenylephrine Hydrochloride in Reducing Symptoms of Common Cold and Flu

Start date: July 2013
Phase: Phase 3
Study type: Interventional

The study is a clinical evaluation of an over the counter (OTC) combination product containing paracetamol (500 mg), dimethindene maleate (1 mg), phenylephrine hydrochloride (10 mg) compared to paracetamol (500 mg) alone in the treatment of nasal congestion, rhinorrhea, sneezing and other symptoms due to upper respiratory tract infection (URTI).

NCT ID: NCT00816972 Completed - Clinical trials for Seasonal Allergic Rhinitis

Desloratadine With Oxybutynin for the Treatment of Seasonal Allergic Rhinitis and Post-Nasal Drip (Study P04258)(COMPLETED)

Start date: April 2005
Phase: Phase 2
Study type: Interventional

This was a 1-week study of desloratadine (DL) plus oxybutynin (OXY) at two dose levels in the treatment of post-nasal drip in participants with seasonal allergic rhinitis. Participants received either desloratadine twice a day, oxybutynin twice a day, desloratadine plus lower-dose oxybutynin twice a day, desloratadine plus higher-dose oxybutynin twice a day, or placebo for 7 days.