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Rhinitis, Allergic clinical trials

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NCT ID: NCT00836914 Completed - Allergic Rhinitis Clinical Trials

Study to Investigate Effects of CAL-101 in Subjects With Allergic Rhinitis Exposed to Allergen in an Environmental Chamber

Start date: February 2009
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the safety and effect of CAL-101 in subjects with allergic rhinitis.

NCT ID: NCT00834119 Completed - Rhinitis, Allergic Clinical Trials

Assessment of Intranasal Steroids in Allergic Rhinitis When Used Alone or in Combination With an Oral Antihistamine (Study P03270)

Start date: September 1, 2003
Phase: Phase 4
Study type: Interventional

This is a Phase 4, non-comparative, open-label, multi-center study. It is designed to determine the effectiveness of regular intranasal steroid use in alleviating allergic rhinitis nasal symptoms, when used alone or in combination with an oral antihistamine. Subjects will receive 200 mcg (2 puffs in each nostril) of mometasone furoate once a day. An oral antihistamine at the discretion of the physician may be added at Day 28 (Visit 2), if patients fail to improve nasal symptoms.

NCT ID: NCT00828061 Completed - Allergic Rhinitis Clinical Trials

A Study of the Effects of Single Dose Corticosteroids on Response to Allergens

Start date: February 4, 2009
Phase: Phase 1
Study type: Interventional

This study will investigate whether changes in inflammatory mediators produced by the nose after exposure to an allergen can be used to evaluate the anti-inflammatory effects of novel drugs for the treatment of allergic asthma.

NCT ID: NCT00824356 Completed - Allergic Rhinitis Clinical Trials

Allergen Challenge Chamber Study With Single Dose Intranasal GSK1004723 Compared With Placebo

Start date: June 2008
Phase: Phase 2
Study type: Interventional

This is a placebo-controlled, 3-period crossover study to assess the efficacy and safety of two single doses of an intranasal anti-histamine GSK1004723 compared with placebo in an allergen challenge chamber in male subjects with seasonal allergic

NCT ID: NCT00817050 Completed - Allergic Rhinitis Clinical Trials

Single Dose Crossover Study of Patient Preference for Unscented Nasonex® Nasal Spray Versus Scented Flonase® Nasal Spray (Study P04207)

Start date: December 1, 2004
Phase: Phase 4
Study type: Interventional

This was a one-day single dose trial conducted to compare patient's preference for Nasonex® (mometasone) versus Flonase® nasal spray. Each patient was randomized to take one dose (2 sprays in each nostril) of Nasonex or Flonase. Thirty minutes later, each patient was to take one dose of the opposite medication. Questionnaires were given to each patient after each drug dose to evaluate patient product preference.

NCT ID: NCT00816972 Completed - Clinical trials for Seasonal Allergic Rhinitis

Desloratadine With Oxybutynin for the Treatment of Seasonal Allergic Rhinitis and Post-Nasal Drip (Study P04258)(COMPLETED)

Start date: April 2005
Phase: Phase 2
Study type: Interventional

This was a 1-week study of desloratadine (DL) plus oxybutynin (OXY) at two dose levels in the treatment of post-nasal drip in participants with seasonal allergic rhinitis. Participants received either desloratadine twice a day, oxybutynin twice a day, desloratadine plus lower-dose oxybutynin twice a day, desloratadine plus higher-dose oxybutynin twice a day, or placebo for 7 days.

NCT ID: NCT00807053 Completed - Clinical trials for Rhinitis, Allergic, Seasonal

Dose-ranging Study to Assess the Efficacy and Safety of Ciclesonide HFA Nasal Aerosol in Adult and Adolescent Patients 12 Years and Older With Seasonal Allergic Rhinitis (SAR) (BY9010/M1-602)

Start date: April 2007
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to demonstrate the efficacy of ciclesonide HFA, applied as a nasal aerosol once daily, in patients with SAR. The secondary objectives are to evaluate Quality-of-Life and safety.

NCT ID: NCT00806754 Completed - Clinical trials for Rhinitis, Allergic, Perennial

Investigation of the Efficacy and Safety of Concomitant Administration of Ciclesonide Nasal Spray and Azelastine Nasal Spray in Patients (18 Years or Older) With Perennial Allergic Rhinitis (PAR) Not Adequately Controlled on an Intranasal Corticosteroid or Antihistamine Monotherapy (BY9010/M1-490)

Start date: November 2006
Phase: Phase 4
Study type: Interventional

- The primary objective of this study is to evaluate the efficacy of the concomitant administration of ciclesonide nasal spray and azelastine nasal spray versus ciclesonide nasal spray alone in patients (18 years or older) with perennial allergic rhinitis (PAR) not adequately controlled on an intranasal corticosteroid or antihistamine monotherapy - The secondary objective is to investigate the safety of the concomitant administration of ciclesonide nasal spray and azelastine nasal spray

NCT ID: NCT00805584 Completed - Clinical trials for Rhinitis, Allergic, Seasonal

Study of Nasal Symptom Relief and Side Effects in Hayfever Patients Treated With Aerius (Desloratadine)(P03442)

Start date: May 2003
Phase: Phase 4
Study type: Interventional

The purpose of this study was to test the effectiveness and side effects of desloratadine (Aerius) in patients with hayfever. Patients took desloratadine once a day for 15 days. At the end of therapy, they scored how severe their hayfever symptoms were and how they responded to therapy. Side effects were recorded.

NCT ID: NCT00805324 Completed - Asthma Clinical Trials

Study of the Effectiveness and Safety of Desloratadine (Aerius) Syrup in Children With Hayfever With or Without Asthma (P03472)

Start date: May 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study was to test the effectiveness and safety of desloratadine (Aerius) syrup in children with hayfever with or without asthma. Patients took desloratadine syrup once a day for 28 days. Once a week, the doctor measured the patient's hayfever symptoms. The doctor also rated how much relief the patient got from treatment and recorded any side effects.