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Rhinitis, Allergic, Seasonal clinical trials

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NCT ID: NCT01230619 Completed - Clinical trials for Seasonal Allergic Rhinitis

Vienna Challenge Chamber Study Using RV658 in Subjects With Allergic Rhinitis

Start date: October 2010
Phase: Phase 2
Study type: Interventional

RV568 is being developed for the treatment of diseases such as asthma, COPD and allergic rhinitis (e.g. hayfever). The main aim of this study is to investigate whether RV568 ameliorates the nasal symptoms to low doses of grass pollen in healthy subjects with seasonal allergic rhinitis.

NCT ID: NCT01224834 Completed - Clinical trials for Rhinitis, Allergic, Seasonal

Safety and Tolerability Study of Ragweed SLIT Tablets

Start date: January 2009
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the safety and tolerability of several doses of ragweed pollen allergen extract administered as sublingual tablets in subjects with allergic rhinitis to ragweed.

NCT ID: NCT01222299 Completed - Clinical trials for Seasonal Allergic Rhinitis

Safety, Pharmacokinetics, and Efficacy of Bepotastine Besilate Nasal Product After Ragweed Pollen Exposure in an Environmental Chamber

Start date: May 2010
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to examine the safety and efficacy of bepotastine besilate nasal product in seasonal allergic rhinitis patients.

NCT ID: NCT01192386 Completed - Clinical trials for Seasonal Allergic Rhinitis

Eosinophil Markers and Development of Disease in Allergic Rhinitis

Start date: May 2010
Phase: N/A
Study type: Observational

Inflammatory proteins from eosinophil granulocytes in blood from patients with seasonal allergic hayfever have been shown to predict development of asthma at a six-year follow-up. This study is a 15-year follow-up of the same patients to verify earlier results and study disease development.

NCT ID: NCT01172613 Recruiting - Clinical trials for Rhinitis, Allergic, Seasonal

Optimal Concentration of Dermatophagoides Pteronyssinus (Dp) Allergen Extract for Skin Prick Test (SPT) of Thai Population

DSPT
Start date: June 2010
Phase: Phase 2/Phase 3
Study type: Observational

The purpose of this study is to determine the appropriate concentration of diagnostic reagent of house dust mite (Dp) to be used in diagnostic allergy skin prick test among Thai population with allergic rhinitis.

NCT ID: NCT01171664 Completed - Clinical trials for Seasonal Allergic Rhinitis

Clinical Trial of STAHIST in Seasonal Allergic Rhinitis (SAR) Subjects

STA-2
Start date: September 2010
Phase: Phase 2
Study type: Interventional

To report and compare total symptom scores, nasal symptom scores, post-nasal drip symptom scores, and adverse reactions in and between SAR subjects on active drug and SAR subjects on placebo.

NCT ID: NCT01137357 Completed - Hay Fever Clinical Trials

Probiotics for Reduction Of Markers In Subjects With Allergy

PROMISA
Start date: November 2008
Phase: N/A
Study type: Interventional

In vitro studies reveal immunomodulatory effects of probiotic bacteria that are strain-dependent. Differential immunomodulatory in vitro capacities can not be extrapolated directly to in vivo efficacy. Thus, in vitro screening should be followed by comparative analysis of the selected immunomodulatory probiotic strains in an in vivo setting. Birch pollen allergy is one of the most common forms of respiratory allergy in European countries, and recognized by a Th2-skewed immune system. Five Lactobacillus strains will be evaluated for their immunomodulatory properties in birch pollen sensitive subjects outside the hay fever season. A double-blind placebo-controlled parallel study will be performed in which subjects with a proven birch pollen allergy will consume one of 5 different probiotic yoghurts containing 4 L. plantarum strains and 1 L. casei strain or a placebo yoghurt. Blood samples are collected at the start and after 4 weeks. Immune parameters are determined in serum and peripheral blood mononuclear cell cultures (hPBMC) derived from these subjects.

NCT ID: NCT01123252 Completed - Asthma Clinical Trials

Seasonal Allergic Rhinitis Study

SAR
Start date: September 2010
Phase: Phase 2
Study type: Interventional

The study aims to examine the effect of probiotics on the clinical symptoms of allergic rhinitis and to elucidate some of the immunological mechanisms involved.

NCT ID: NCT01108783 Completed - Clinical trials for Seasonal Allergic Rhinitis

A Phase III Efficacy Study of the Symptomatic Treatment of Seasonal Allergic Rhinitis With Bilastine

Start date: April 2003
Phase: Phase 3
Study type: Interventional

The objective of the study was to determine the efficacy and tolerability of 20 mg of Bilastine, compared to Desloratadine and placebo for the treatment of Seasonal Allergic Rhinitis.

NCT ID: NCT01103934 Completed - Clinical trials for Seasonal Allergic Rhinitis

Vitamin D Plus Fluticasone Propionate

Start date: June 2010
Phase: Phase 4
Study type: Interventional

The objectives of this study would be to see if the addition of vitamin D to fluticasone propionate provides greater symptomatic relief in patients with seasonal allergic rhinitis compared to fluticasone propionate treatment alone.