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NCT03784261 Clinical Trial

Usefulness of Non TNF Usage in RA Patients

Rheumatoid Arthritis Clinical Trial

Official title:
Usefulness of Non TNF Usage in Rheumatoid Arthritis Patients

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT03784261
Other study ID # NonTNF 2018
Secondary ID
Status Recruiting
Phase Phase 2
First received
Last updated
Start date December 17, 2018
Est. completion date December 16, 2024

Study information
Verified date September 2021
Source Shinshu University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The aim of this study is to examine the efficacy and adverse events in the following 3 groups in rheumatoid arthritis patients: 1. Sarilumab treatment for 12 months 2. Tocilizmab treatment for 12 months 3. Abatacept treatment for 12 months

Recruitment information / eligibility
Status Recruiting
Enrollment 90
Est. completion date December 16, 2024
Est. primary completion date December 16, 2022
Accepts healthy volunteers No
Gender All
Age group 20 Years to 100 Years
Eligibility Inclusion Criteria: ·RA patients Exclusion Criteria: - Not RA patients - RA patients who are allergic to the drugs, refused to do this research, or who are pregnant

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Drug: "Salirumab"
To examine the effects of salirumab in RA patients
• Drug: "Tocilizmab"
To examine the effects of tocilizmab in RA patients
• Drug: "Abatacept"
To examine the effects of abatacept in RA patients

Locations
Country Name City State
Japan Yukio Nakamura Matsumoto Nagano

Sponsors (1)
Lead Sponsor Collaborator
Shinshu University

Country where clinical trial is conducted

Japan, 

Outcome
Type Measure Description Time frame Safety issue
Primary Change from Baseline Values of DAS28-CRP Assessment of efficacy in rheumatoid arthritis patients for 1 year treated by salirumab (N=30), tocilizumab (N=30), or abatacept (N=30). Baseline and 1 year
Primary Assessment of adverse event in rheumatoid arthritis patients for 1 year treated by salirumab (N=30), tocilizumab (N=30), or abatacept (N=30). at 1 year
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