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Rheumatoid Arthritis clinical trials

View clinical trials related to Rheumatoid Arthritis.

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NCT ID: NCT01569074 Terminated - Clinical trials for Rheumatoid Arthritis

Evaluation of Safety and Effectiveness of Fostamatinib Compared to Placebo in Patients in Asia With Rheumatoid Arthritis

OSKIRA-Asia-1
Start date: April 2012
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate the effectiveness of four dosing regimens of fostamatinib compared to placebo, in patients with rheumatoid arthritis (RA) who are taking methotrexate but not responding. The study will last for 12 weeks.

NCT ID: NCT01567358 Completed - Clinical trials for Rheumatoid Arthritis

Study of NI-071 in Comparison With Remicade in Patients With Rheumatoid Arthritis

Start date: February 2012
Phase: Phase 1
Study type: Interventional

The purpose of this study is to compare the safety of NI-071 with Remicade® (infliximab) in patients with Rheumatoid Arthritis inadequately treated with Methotrexate.

NCT ID: NCT01566201 Completed - Clinical trials for Coronary Artery Disease

Effects of Interleukin-1 Inhibition on Vascular and Left Ventricular Function in Rheumatoid Arthritis Patients With Coronary Artery Disease

Start date: March 2011
Phase: N/A
Study type: Interventional

Inhibition of interleukin-1 (IL-1) activity in patients with RA without CAD ameliorates vascular and LV function. Moreover, data from species shows beneficial effect of this treatment on LV function after experimental myocardial infarction. The purpose of this study is to investigate whether anakinra, an IL-1 receptor antagonist, improves vascular and left ventricular (LV) function in patients with coronary artery disease (CAD) and coexistent rheumatoid arthritis (RA).

NCT ID: NCT01565408 Completed - Clinical trials for Rheumatoid Arthritis

Safety and Tolerability of NNC0114-0006 at Increasing Dose Levels in Subjects With Rheumatoid Arthritis

Start date: March 2012
Phase: Phase 1
Study type: Interventional

This trial is conducted in Europe. The aim of this dose-escalating trial is to assess the safety and tolerability of multiple doses of NNC0114-0006 in subjects with rheumatoid arthritis (RA).

NCT ID: NCT01565122 Completed - Clinical trials for Rheumatoid Arthritis

An Observational Study in Rheumatoid Arthritis Patients Treated With RoActemra/Actemra (Tocilizumab)

Start date: March 2012
Phase: N/A
Study type: Observational

This multi-center, observational study will evaluate the clinical practice patterns, efficacy and safety of RoActemra/Actemra (tocilizumab) in patients with rheumatoid arthritis. Data will be collected from each eligible patient initiated on RoActemra/Actemra treatment by their treating physician according to approved label for up to 12 months from start of treatment.

NCT ID: NCT01564901 Completed - Clinical trials for Rheumatoid Arthritis

An Observational Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis Treated With Glucocorticoids

Start date: January 2012
Phase: N/A
Study type: Observational

This prospective, observational, multicenter study will assess the efficacy and safety of RoActemra/Actemra (tocilizumab) on the use of glucocorticoids in patients with moderate to severe rheumatoid arthritis and an inadequate response to previous disease-modifying antirheumatic drugs or anti-TNF. Data will be collected for 36 weeks.

NCT ID: NCT01564147 Terminated - Clinical trials for Rheumatoid Arthritis

More Added Value of Therapeutic Education in the Management of Patients With Rheumatoid Arthritis (ETP-PR)

ETP-PR
Start date: September 2011
Phase: N/A
Study type: Interventional

Taking into account the recommendations of the Health Authority [1] and the application of patients' associations, we have structured a course of therapeutic education includes three stages for patients with rheumatoid arthritis and followed at Nantes University Hospital. Step 1: initial interview with a nurse patient education for diagnosis and education with the patient to choose three subjects from among 10 offered him problematic; Step 2: Orientation in an educational path that provides access to 6 months group workshops (3 maximum) and / or interviews tailored to the three selected topics; Step 3: final interview with a nurse said therapeutic education formative assessment to take stock. The main objective of our work is to ensure that the patient finds it easier solutions to the three problematic topics him after 6 months of education after six months without treatment.

NCT ID: NCT01563978 Completed - Clinical trials for Rheumatoid Arthritis

Study of the Effect of Fostamatinib Twice Daily on Blood Pressure in Patients With Rheumatoid Arthritis

Oskira ABPM
Start date: April 2012
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the effect of fostamatinib compared to placebo on ambulatory blood pressure in patients with active rheumatoid arthritis who are taking a disease-modifying anti-rheumatic drug (DMARD). The study will last for 57 days.

NCT ID: NCT01562327 Completed - Clinical trials for Rheumatoid Arthritis

A Non-interventional Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis

Start date: March 2012
Phase: N/A
Study type: Observational

This multi-center, observational study will evaluate the clinical practice patterns, efficacy and safety of RoActemra/Actemra (tocilizumab) in patients with moderate to severe rheumatoid arthritis. Data will be collected from each eligible patient initiated on RoActemra/Actemra treatment by their treating physician according to local label for 6 months from start of treatment.

NCT ID: NCT01561313 Completed - Clinical trials for Rheumatoid Arthritis

Crossover Study of Safety and Tolerability of Two Formulations of Adalimumab.

Start date: March 2012
Phase: Phase 2
Study type: Interventional

This study will compare injection site pain levels between current Humira® formulation versus a new formulation of Humira in patients with Rheumatoid Arthritis (RA), who are either currently on a stable dose (minimum six consecutive doses) of on-label Humira or biological naïve who will be prescribed on-label Humira as treatment for their Rheumatoid Arthritis. The study is being conducted in two countries, Belgium (3 sites) and the Czech Republic (3 sites).