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NCT02360436 Clinical Trial

Analysis of the Glutathione Cycle in Children With Rett Syndrome

Rett Syndrome Clinical Trial

Official title:
EPITRA-14-001: Analysis of the Glutathione Cycle in Children With Rett Syndrome

Clinical Trial Details — Status: Withdrawn

Administrative data
NCT number NCT02360436
Other study ID # EPITRA-14-001
Secondary ID
Status Withdrawn
Phase
First received
Last updated
Start date March 31, 2015
Est. completion date September 30, 2015

Study information
Verified date January 2022
Source Edison Pharmaceuticals Inc
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Analyis of the Glutathione Cycle in Children with Rett Syndrome

Description:

To analyze the levels of glutathione and relevant glutathione metabolites in children with Rett syndrome in an effort to better understand disease pathology and biochemistry.

Recruitment information / eligibility
Status Withdrawn
Enrollment 0
Est. completion date September 30, 2015
Est. primary completion date July 31, 2015
Accepts healthy volunteers No
Gender All
Age group 2 Years to 10 Years
Eligibility Inclusion Criteria: - Age between 2 and 10, inclusive - Genetically-confirmed diagnosis of Rett syndrome with MeCP2 mutation - No change in dietary supplements in three months prior to the initial blood draw - No participation in interventional pharmaceutical clinical trials in prior 12 months Exclusion Criteria: - None other than meeting Inclusion criteria

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United States University of Alabama, Birmingham Birmingham Alabama

Sponsors (1)
Lead Sponsor Collaborator
Edison Pharmaceuticals Inc

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Analysis of changes in levels of glutathione and relevant glutathione metabolites in children with Rett syndrome from baseline to the end of month 6 6 months
See also
  Status Clinical Trial Phase
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Enrolling by invitation NCT06139172 - Promoting Prosocial Behavior in Syndromic Intellectual and Developmental Disabilities N/A
Not yet recruiting NCT04041713 - A Pilot Study of an Antioxidant Cocktail vs. Placebo in the Treatment of Children and Adolescents With Rett Syndrome Phase 2
Not yet recruiting NCT04014985 - Patients With RETT Syndrome N/A
Completed NCT02705677 - Biobanking of Rett Syndrome and Related Disorders
Terminated NCT02790034 - Evaluation of the Efficacy, Safety, and Tolerability of Sarizotan in Rett Syndrome With Respiratory Symptoms Phase 2/Phase 3
Enrolling by invitation NCT03655223 - Early Check: Expanded Screening in Newborns
Recruiting NCT05932589 - Neurophysiologic Biomarkers in Rett Syndrome
Recruiting NCT04463316 - GROWing Up With Rare GENEtic Syndromes
Completed NCT04776746 - Open-Label Extension Study of Trofinetide for Rett Syndrome Phase 3
Completed NCT04181723 - Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome (LAVENDER™) Phase 3
Enrolling by invitation NCT03836300 - Parent and Infant Inter(X)Action Intervention (PIXI) N/A
Completed NCT04514549 - ASSESSING EMERALD AND MC10 BIOSTAMP nPOINT BIOSENSORS FOR RETT SYNDROME
Completed NCT02738281 - Natural History of Rett Syndrome & Related Disorders
Terminated NCT02562820 - An Exploratory Trial of Ketamine for the Treatment of Rett Syndrome Phase 1
Completed NCT05687214 - Osteopathic Manipulative Treatment for Constipation in People With Rett Syndrome N/A
Recruiting NCT06199700 - Esketamine for the Treatment of Rett Syndrome Early Phase 1
Completed NCT03941444 - ANAVEX2-73 Study in Patients With Rett Syndrome Phase 3
Recruiting NCT06346106 - The Diagnostic Experience of Male Rett Syndrome

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