Aortitis and Retroperitoneal Fibrosis: Evaluation of Diagnostic Criteria

Retroperitoneal Fibrosis Clinical Trial

Official title:

Aortitis and Retroperitoneal Fibrosis: Evaluation of Diagnostic Criteria

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03133949
• Other study ID #: PHRCIR09-DR-SCHMIDT
• Status: Recruiting
• Phase: N/A
• First received: April 13, 2017
• Last updated: April 25, 2017
• Start date: July 8, 2010
• Est. completion date: July 8, 2020

Study information

• Verified date: April 2017
• Source: Centre Hospitalier Universitaire, Amiens
• Contact: Jean SCHMIDT, PhD
• Phone: +33322668230
• Email: schmidt.jean[@]chu-amiens.fr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Inflammatory aortitis probably represents a heterogeneous group, and the clinical experience accumulated over the last ten years, shared by the experts of the subject, is that the initial clinical, biological or radiological characteristics should make it possible to differentiate them and dismember the Nosological field.

This will be an essential first step before studying prognosis, risk factors, and therapeutic options.

The search for diagnostic criteria on a large series, similar to the study of classification of vascularites of the ACR in 1990, should make it possible to homogenize the diagnoses for the different teams working on the subject, and to begin work Collaborations, which alone can improve patient care in the future.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 206
• Est. completion date: July 8, 2020
• Est. primary completion date: July 8, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Cases :

• All cases of idiopathic aortitis and retroperitoneal fibrosis followed in participating centers over the past 15 years will be collected.

• Witnesses :

• Group 1: non-idiopathic inflammatory aortitis: all cases of inflammatory aortitis (apart from idiopathic aortites and isolated retroperitoneal fibrosis) followed in the participating centers over the last 15 years will be collected.

• Group 2: subjects with noninflammatory aortic disease, atheromatous type or annulo-ectasitic disease, matched by age and sex with cases. This group will be used to define the differential characteristics between idiopathic aortitis and noninflammatory aortic pathology.

• Group 3: This group will include control subjects aimed at defining radiological normality criteria according to age and sex. As the images are machine-dependent, group 3 controls will be randomly selected from the radiology departments that have performed the scanner or MRI of the corresponding control.

Exclusion Criteria:

• Patients under 18 years of age

Related Conditions & MeSH terms

• Aortitis
• Fibrosis
• Idiopathic Aortitis
• Retroperitoneal Fibrosis

Intervention

Other:
• Establish the clinical, biological and radiological characteristics of patients
Establish the clinical, biological and radiological characteristics of patients

Locations

Country	Name	City	State
France	CHU Amiens Picardie	Amiens	Picardie

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire, Amiens

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Analyze the management of patients with aortic and retroperitoneal fibrosis		1 day