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NCT00461435 Clinical Trial

Slowing the Degenerative Process, Long Lasting Effect of Hyperbaric Oxygen Therapy in Retinitis Pigmentosa

Retinitis Pigmentosa Clinical Trial

Official title:
Slowing the Degenerative Process, Long Lasting Effect of Hyperbaric Oxygen Therapy in Retinitis Pigmentosa

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00461435
Other study ID # SS01
Secondary ID
Status Completed
Phase N/A
First received April 17, 2007
Last updated April 17, 2007

Study information
Verified date April 2007
Source Azienda Policlinico Umberto I
Contact n/a
Is FDA regulated No
Health authority Italy:Italian National commitee for hyperbaric therapy
Study type Interventional

Clinical Trial Summary

Our aim was to assess the role and usefulness of Hyperbaric oxygen therapy in a long lasting period, assessing its efficacy on rescuing retinal photoreceptors and preserving visual function in retinitis pigmentosa.

Recruitment information / eligibility
Status Completed
Enrollment 0
Est. completion date
Est. primary completion date
Accepts healthy volunteers
Gender Both
Age group 20 Years to 70 Years
Eligibility Inclusion Criteria:

- Patients with clearly hereditary RP (we performed to all of them genetic analysis for rhodopsin, and peripherin genes, only 4 patient with ADRP showed point mutation 3 on codon 135 and 1 on codon 347); best corrected visual acuity (BCVA) = 0.50 logMAR; visual field = 3 degree diameter circle; recordable ERG.

Exclusion Criteria:

- Exclusion criteria were: patients with sporadic RP; BCVA = 0.50 logMAR; visual field = 3 degree diameter circle; not recordable ERG.

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind

Related Conditions & MeSH terms

Intervention

Procedure:
• hyperbaric oxygen therapy

Locations
Country Name City State
Italy Azienda Policlinico Umberto I Rome

Sponsors (1)
Lead Sponsor Collaborator
Azienda Policlinico Umberto I

Country where clinical trial is conducted

Italy, 

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