Retinitis Pigmentosa Syndrome Clinical Trial
Official title:
Evaluation of the Visual Field on the Ground: Impact on Locomotion Rehabilitation Adults With Retinitis Pigmentosa With Loss of Peripheral Vision
Retinopathy pigmentosa (which affects about 40,000 patients in France) leads to destruction
of the peripheral retina. This condition, often familial, frequently affects young patients.
Visual acuity is excellent for a long time, the disease affecting the central macular region
only belatedly. On the other hand, the visual field is very quickly narrowed to a central or
paracentral zone.
For the patient, knowing the limits of his visual field and learning to adapt is necessary
especially when traveling.
The management of these patients is twofold:
- an orthoptist carries out an overall evaluation of the visual field using the Goldmann
device (30 cm projection of the areas seen and not seen by the patient's eye), then
performs rehabilitation over several weeks
- an instructor of locomotion (open specialization: occupational therapist, case of this
project,...) carries out an evaluation in situation, followed by a personalized
reeducation over several weeks. The first sessions consist in establishing a climate of
confidence, presenting the objectives of the management of locomotion and begin to
understand the movements inside and outside accompanied. The following of the
rehabilitation is an apprenticeship of the optimal use of the residual field of vision
and the proposed technical aids (white cane), in the whole of the displacements, inside
and outside.
The residual field of vision is evaluated by a device at the first appointment at the
specialized center. This examination, necessary for the professional, is not informative for
the patient. It is sometimes supplemented by the evaluation of the visual field of view
(ECVS). The ECVS, done jointly by the orthoptist and the locomotion instructor, consists in
evaluating the functional visual field on a horizontal plane at 1m (meter) and 5m, and
vertical at 5m. The field of vision of the patient, immobile, is materialized by targets
deposited at each limit of the zones seen that it indicates.
The investigators believe that the passing of a visual field on the ground, thanks to the
projection of the zones of vision, allows the patient to improve his knowledge on his visual
possibilities (and gaps) and thus to make his reeducation more efficient.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT05392751 -
Dose Escalation Study to Evaluate the Safety/Tolerability and Efficacy of EA-2353 in Subjects With Retinitis Pigmentosa
|
Phase 1/Phase 2 |